iPTMnet Report for Q5T2W1 (PDZK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T2W1 / NHRF3_HUMAN
Protein Name Na(+)/H(+) exchange regulatory cofactor NHE-RF3
Gene Name Name: PDZK1
Synonyms:CAP70,NHERF3,PDZD1;
Organism Homo sapiens (Human)

PRO ID PR:Q5T2W1
DAG View
PRO Name Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (human)
Definition A Na(+)/H(+) exchange regulatory cofactor NHE-RF3 that is encoded in the genome of human.
Short Label hPDZK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T2W1 (PDZK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus   UniProt 24275569
S250 Phosphorylation PhosphoSitePlus
Y328 Phosphorylation PhosphoSitePlus
T480 Phosphorylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus   RLIMS-P 21653824, 20949066
T506 Phosphorylation PhosphoSitePlus
S508 Phosphorylation PhosphoSitePlus
S510 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S508 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S511 F511 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]