iPTMnet Report for Q5T280 (SPOUT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T280 / CI114_HUMAN
Protein Name Putative methyltransferase C9orf114
Gene Name Name: SPOUT1
Synonyms:C9orf114;
Organism Homo sapiens (Human)

PRO ID PR:Q5T280
DAG View
PRO Name putative methyltransferase C9orf114 (human)
Definition A putative methyltransferase C9orf114 that encoded in the genome of human.
Short Label hSPOUT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T280 (SPOUT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K39 Acetylation PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K123 Sumoylation PhosphoSitePlus
K134 Acetylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
T241 Phosphorylation PhosphoSitePlus
Y242 Phosphorylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
S294 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K135 R135 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K162 E162 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S177 N177 Biomuta DOID:2394 / ovarian cancer [ cosmic ]