Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T1R4 / ZEP3_HUMAN
Protein Name Transcription factor HIVEP3
Gene Name Name: HIVEP3
Synonyms:KBP1,KIAA1555,KRC,ZAS3;
Organism Homo sapiens (Human)

PRO ID PR:Q5T1R4
DAG View
PRO Name transcription factor HIVEP3 (human)
Definition A transcription factor HIVEP3 that is encoded in the genome of human.
Short Label hHIVEP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T1R4 (HIVEP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K182 Acetylation PhosphoSitePlus
T215 Phosphorylation PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus
S405 Phosphorylation PhosphoSitePlus
S489 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
S495 Phosphorylation PhosphoSitePlus
T516 O-Glycosylation GlyGen 31492838, 29351928, 28657654, ...35254053
T531 O-Glycosylation GlyGen 29351928, 31492838, 32938750, ...28657654, 35254053
S542 Phosphorylation IntAct   PhosphoSitePlus 34341191
S545 Phosphorylation PhosphoSitePlus
K611 Acetylation PhosphoSitePlus
K624 Acetylation PhosphoSitePlus
K634 Acetylation PhosphoSitePlus
K637 Acetylation PhosphoSitePlus
K639 Acetylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus
T710 Phosphorylation PhosphoSitePlus
S720 Phosphorylation PhosphoSitePlus
S732 Phosphorylation PhosphoSitePlus
T733 Phosphorylation PhosphoSitePlus
S739 Phosphorylation PhosphoSitePlus
S763 O-Glycosylation GlyGen 29351928, 31492838, 32938750, ...28657654, 35254053
S766 O-Glycosylation GlyGen 31492838, 29351928, 28657654, ...35254053
T777 Phosphorylation PhosphoSitePlus
S782 Phosphorylation PhosphoSitePlus
S784 Phosphorylation PhosphoSitePlus
S786 Phosphorylation PhosphoSitePlus
K788 Acetylation PhosphoSitePlus
T869 Phosphorylation PhosphoSitePlus
S890 O-Glycosylation GlyGen 32938750
S931 Phosphorylation PhosphoSitePlus
S933 Phosphorylation PhosphoSitePlus
S939 Phosphorylation PhosphoSitePlus
S943 Phosphorylation PhosphoSitePlus
S944 Phosphorylation PhosphoSitePlus
S948 Phosphorylation PhosphoSitePlus
S961 Phosphorylation PhosphoSitePlus
S993 Phosphorylation PhosphoSitePlus
S1012 Phosphorylation PhosphoSitePlus
S1050 Phosphorylation PhosphoSitePlus
S1069 Phosphorylation PhosphoSitePlus
S1075 O-Glycosylation GlyGen 31492838, 29351928, 28657654, ...35254053
S1076 O-Glycosylation GlyGen 31492838, 29351928, 28657654, ...35254053
S1077 O-Glycosylation GlyGen 31492838, 29351928, 28657654, ...35254053
S1080 O-Glycosylation GlyGen 31492838, 29351928, 28657654, ...35254053
S1089 O-Glycosylation GlyGen 29351928, 31492838, 32938750, ...28657654, 35254053
S1094 O-Glycosylation GlyGen 29351928, 31492838, 32938750, ...28657654, 35254053
S1296 O-Glycosylation GlyGen 32938750
T1344 O-Glycosylation GlyGen 32938750
T1401 O-Glycosylation GlyGen 31492838, 29351928, 28657654, ...35254053
S1409 O-Glycosylation GlyGen 31492838, 29351928, 28657654, ...35254053
S1433 Phosphorylation PhosphoSitePlus
S1437 Phosphorylation PhosphoSitePlus
S1456 Phosphorylation PhosphoSitePlus
S1528 O-Glycosylation GlyGen 32938750
T1547 Phosphorylation PhosphoSitePlus
S1550 Phosphorylation PhosphoSitePlus
S1570 O-Glycosylation GlyGen 31492838, 29351928, 28657654, ...35254053
S1574 O-Glycosylation GlyGen 32938750
Y1737 Phosphorylation PhosphoSitePlus
Y1743 Phosphorylation PhosphoSitePlus
Y1745 Phosphorylation PhosphoSitePlus
T1775 Phosphorylation PhosphoSitePlus
T1777 Phosphorylation PhosphoSitePlus
S1908 O-Glycosylation GlyGen 32938750
T1913 O-Glycosylation GlyGen 32938750
S1919 O-Glycosylation GlyGen 31492838, 29351928, 28657654, ...35254053
S1928 O-Glycosylation GlyGen 32938750
S1964 Phosphorylation PhosphoSitePlus
S1970 Phosphorylation PhosphoSitePlus
S1986 Phosphorylation PhosphoSitePlus
S2006 O-Glycosylation GlyGen 32938750
S2006 Phosphorylation PhosphoSitePlus
S2009 Phosphorylation PhosphoSitePlus
S2034 Phosphorylation PhosphoSitePlus
S2067 Phosphorylation PhosphoSitePlus
S2127 Phosphorylation PhosphoSitePlus
S2133 Phosphorylation PhosphoSitePlus
S2245 Phosphorylation PhosphoSitePlus
S2251 Phosphorylation PhosphoSitePlus
S2253 Phosphorylation PhosphoSitePlus
S2255 Phosphorylation PhosphoSitePlus
S2329 Phosphorylation PhosphoSitePlus
R2331 Methylation PhosphoSitePlus
T2346 Phosphorylation PhosphoSitePlus
S2354 Phosphorylation PhosphoSitePlus
S2373 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S784 Phosphorylation HPRD 18452278
S786 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K363 N363 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S492 P492 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K637 N637 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S720 R720 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S732 C732 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S766 F766 Biomuta DOID:4159 / skin cancer [ cosmic ]
S784 L784 Biomuta DOID:4159 / skin cancer [ cosmic ]
S939 F939 Biomuta DOID:4159 / skin cancer [ cosmic ]
S948 L948 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
S1012 Y1012 Biomuta DOID:363 / uterine cancer [ icgc ]
S1050 F1050 Biomuta [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
S1076 F1076 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1089 F1089 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1437 I1437 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1550 N1550 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1574 L1574 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y1737 C1737 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1908 Y1908 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S1919 L1919 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1964 F1964 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1964 P1964 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1986 L1986 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S2067 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S2127 N2127 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S2133 F2133 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S2255 L2255 Biomuta [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S2329 G2329 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R2331 H2331 Biomuta DOID:9256 / colorectal cancer [ cosmic ]