iPTMnet Report for Q5T0W9 (FAM83B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T0W9 / FA83B_HUMAN
Protein Name Protein FAM83B
Gene Name Name: FAM83B
Synonyms:C6orf143;
Organism Homo sapiens (Human)

PRO ID PR:Q5T0W9
DAG View
PRO Name protein FAM83B (human)
Definition A protein FAM83B that is encoded in the genome of human.
Short Label hFAM83B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T0W9 (FAM83B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation HPRD   PhosphoSitePlus 20068231
S8 Phosphorylation PhosphoSitePlus
S9 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y63 Phosphorylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
T171 Phosphorylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
S311 Phosphorylation PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
S334 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19691289
S335 Phosphorylation PhosphoSitePlus
Y336 Phosphorylation PhosphoSitePlus
K338 Methylation PhosphoSitePlus
Y343 Phosphorylation PhosphoSitePlus
T344 Phosphorylation PhosphoSitePlus
Y351 Phosphorylation PhosphoSitePlus
Y358 Phosphorylation PhosphoSitePlus
R373 Methylation PhosphoSitePlus
K385 Methylation PhosphoSitePlus
S388 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
Y389 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
Y399 Phosphorylation PhosphoSitePlus
K418 Acetylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
S422 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S424 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S427 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S429 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
Y433 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
T439 Phosphorylation PhosphoSitePlus
T453 Phosphorylation PhosphoSitePlus
T454 Phosphorylation PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus
S466 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19691289, ...20068231
T470 Phosphorylation PhosphoSitePlus
T483 Phosphorylation PhosphoSitePlus
Y523 Phosphorylation PhosphoSitePlus
K530 Methylation PhosphoSitePlus
Y535 Phosphorylation PhosphoSitePlus
S538 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus   UniProt 23186163
T583 Phosphorylation PhosphoSitePlus
S598 Phosphorylation PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus
T632 Phosphorylation PhosphoSitePlus
S634 Phosphorylation PhosphoSitePlus
Y637 Phosphorylation PhosphoSitePlus
Y639 Phosphorylation PhosphoSitePlus
K652 Methylation PhosphoSitePlus
K661 Methylation PhosphoSitePlus
K661 Ubiquitination PhosphoSitePlus
S664 O-Glycosylation GlyGen 30379171
S664 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19691289, ...20068231
S671 Phosphorylation PhosphoSitePlus
K672 Methylation PhosphoSitePlus
S680 Phosphorylation PhosphoSitePlus
Y683 Phosphorylation PhosphoSitePlus
Y685 Phosphorylation PhosphoSitePlus
S686 Phosphorylation PhosphoSitePlus
T687 Phosphorylation PhosphoSitePlus
K705 Methylation PhosphoSitePlus
S709 Phosphorylation PhosphoSitePlus
S729 Phosphorylation PhosphoSitePlus
T733 Phosphorylation PhosphoSitePlus
S739 Phosphorylation PhosphoSitePlus
S751 Phosphorylation PhosphoSitePlus
S764 Phosphorylation HPRD   PhosphoSitePlus 19691289, 20068231
S766 Phosphorylation PhosphoSitePlus
S777 Phosphorylation PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus
T782 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
Y798 Phosphorylation PhosphoSitePlus
S802 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S803 Phosphorylation PhosphoSitePlus
S804 Phosphorylation PhosphoSitePlus
T806 Phosphorylation PhosphoSitePlus
S809 Phosphorylation PhosphoSitePlus
S833 Phosphorylation PhosphoSitePlus
S836 Phosphorylation PhosphoSitePlus
S838 Phosphorylation PhosphoSitePlus
S841 Phosphorylation PhosphoSitePlus
S845 Phosphorylation PhosphoSitePlus
T850 Phosphorylation PhosphoSitePlus
S852 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
T867 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S869 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19007248, ...19691289
S875 Phosphorylation PhosphoSitePlus
S885 Phosphorylation PhosphoSitePlus
Y896 Phosphorylation PhosphoSitePlus
S899 Phosphorylation PhosphoSitePlus
T907 Phosphorylation PhosphoSitePlus
T913 Phosphorylation PhosphoSitePlus
S914 Phosphorylation PhosphoSitePlus
S915 Phosphorylation PhosphoSitePlus   UniProt 23186163
S920 Phosphorylation PhosphoSitePlus
S928 Phosphorylation PhosphoSitePlus
T929 Phosphorylation PhosphoSitePlus
Y934 Phosphorylation PhosphoSitePlus
K964 Methylation PhosphoSitePlus
S965 Phosphorylation PhosphoSitePlus
T967 Phosphorylation PhosphoSitePlus
S971 Phosphorylation PhosphoSitePlus
Y972 Phosphorylation PhosphoSitePlus
R974 Methylation PhosphoSitePlus
S976 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
Y981 Phosphorylation PhosphoSitePlus
Y986 Phosphorylation PhosphoSitePlus
R987 Methylation PhosphoSitePlus
R997 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S5 L5 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S8 F8 Biomuta DOID:4159 / skin cancer [ cosmic ]
S8 Y8 Biomuta DOID:1324 / lung cancer [ cosmic ]
S9 L9 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S175 F175 Biomuta DOID:4159 / skin cancer [ cosmic ]
S175 Y175 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S309 L309 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S311 F311 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S312 L312 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S317 F317 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S318 R318 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S334 F334 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S335 N335 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y343 C343 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S388 I388 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K418 N418 Biomuta DOID:363 / uterine cancer [ icgc ]
K418 T418 Biomuta DOID:4159 / skin cancer [ cosmic ]
S424 I424 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S424 R424 Biomuta DOID:363 / uterine cancer [ icgc ]
S429 P429 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S429 L429 Biomuta DOID:4159 / skin cancer [ cosmic ]
S429 * Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
T439 A439 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S466 F466 Biomuta [ cosmic ]
T483 A483 Biomuta DOID:4159 / skin cancer [ cosmic ]
S543 P543 Biomuta DOID:3571 / liver cancer [ cosmic ]
S543 Y543 Biomuta DOID:4159 / skin cancer [ cosmic ]
S543 T543 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S543 F543 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S621 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S634 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
Y639 H639 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K652 N652 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K652 R652 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K652 T652 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S671 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S686 N686 Biomuta DOID:1324 / lung cancer [ cosmic ]
T687 I687 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S709 G709 Biomuta DOID:3571 / liver cancer [ cosmic ]
S729 F729 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T733 A733 Biomuta DOID:1324 / lung cancer [ cosmic ]
S739 F739 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S777 L777 Biomuta DOID:4159 / skin cancer [ cosmic ]
S780 R780 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S802 G802 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S804 F804 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S833 C833 Biomuta DOID:4159 / skin cancer [ cosmic ]
S836 L836 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S838 Y838 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S841 T841 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T850 I850 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S885 F885 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S899 L899 Biomuta DOID:4159 / skin cancer [ cosmic ]
S899 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T907 N907 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
T913 A913 Biomuta DOID:4362 / cervical cancer [ icgc ] DOID:10283 / prostate cancer [ cosmic, icgc ]
S914 T914 Biomuta DOID:1324 / lung cancer [ cosmic ]
S915 P915 Biomuta DOID:4159 / skin cancer [ cosmic ]
S920 F920 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T929 S929 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y934 H934 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T967 A967 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R974 M974 Biomuta DOID:1324 / lung cancer [ cosmic ]
R987 C987 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic ]
R987 H987 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
R997 L997 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R997 * Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
R997 Q997 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic, icgc ]