iPTMnet Report for Q5T0T0 (MARCHF8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T0T0 / MARH8_HUMAN
Protein Name E3 ubiquitin-protein ligase MARCHF8
Gene Name Name: MARCHF8
Synonyms:MARCH8,MIR,RNF178;
Organism Homo sapiens (Human)

PRO ID PR:Q5T0T0
DAG View
PRO Name E3 ubiquitin-protein ligase MARCHF8 (human)
Definition An E3 ubiquitin-protein ligase MARCHF8 that is encoded in the genome of human.
Short Label hMARCHF8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T0T0 (MARCHF8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S71 Phosphorylation PhosphoSitePlus
Y237 Phosphorylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus   UniProt 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S253 Y253 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S253 F253 Biomuta DOID:363 / uterine cancer [ icgc ]