iPTMnet Report for Q5SZL2 (CEP85L)
Protein Information
| UniProt AC / UniProt ID | Q5SZL2 / CE85L_HUMAN |
| Protein Name | Centrosomal protein of 85 kDa-like |
| Gene Name | Name: CEP85L Synonyms:C6orf204; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q5SZL2 |
| PRO Name | centrosomal protein of 85 kDa-like (human) |
| Definition | A centrosomal protein of 85 kDa-like that is encoded in the genome of human. |
| Short Label | hCEP85L |
| Category | organism-gene |
Q5SZL2 (CEP85L) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S11 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S15 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K113 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S117 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T119 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T132 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S137 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K148 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K161 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K190 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S207 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| R212 | Methylation | score1 | PhosphoSitePlus | |||
| K231 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K237 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S243 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T246 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T314 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S317 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S351 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K359 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K367 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K374 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K382 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K453 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K463 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K537 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K586 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K621 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K646 | Acetylation | score1 | PhosphoSitePlus | |||
| K653 | Acetylation | score1 | PhosphoSitePlus | |||
| K670 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K740 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S756 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S137 | G137 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K185 | N185 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K231 | T231 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S351 | L351 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| K359 | R359 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| K374 | R374 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| K621 | M621 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K646 | Q646 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| K740 | M740 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K740 | N740 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
DAG View