Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5SZK8 / FREM2_HUMAN
Protein Name FRAS1-related extracellular matrix protein 2 precursor
Gene Name Name: FREM2
Organism Homo sapiens (Human)

PRO ID PR:Q5SZK8
DAG View
PRO Name FRAS1-related extracellular matrix protein 2 (human)
Definition A FRAS1-related extracellular matrix protein 2 that is encoded in the genome of human.
Short Label hFREM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5SZK8 (FREM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S57 Phosphorylation PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
K125 Acetylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
Y786 Phosphorylation PhosphoSitePlus
T797 Phosphorylation PhosphoSitePlus
S880 Phosphorylation PhosphoSitePlus
T982 Phosphorylation PhosphoSitePlus
S1134 Phosphorylation PhosphoSitePlus
T1291 Phosphorylation PhosphoSitePlus
T1303 Phosphorylation PhosphoSitePlus
T1319 Phosphorylation PhosphoSitePlus
S1525 Phosphorylation PhosphoSitePlus
S1527 Phosphorylation PhosphoSitePlus
T1537 Phosphorylation PhosphoSitePlus
N1741 N-Glycosylation UniProt 16335952
Y1796 Phosphorylation PhosphoSitePlus
T1800 Phosphorylation PhosphoSitePlus
S1804 Phosphorylation PhosphoSitePlus
T2035 Phosphorylation PhosphoSitePlus
T2044 Phosphorylation PhosphoSitePlus
S2047 Phosphorylation PhosphoSitePlus
T2050 Phosphorylation PhosphoSitePlus
T2059 Phosphorylation PhosphoSitePlus
Y2061 Phosphorylation PhosphoSitePlus
S2065 Phosphorylation PhosphoSitePlus
Y2137 Phosphorylation PhosphoSitePlus
T2138 Phosphorylation PhosphoSitePlus
S2140 Phosphorylation PhosphoSitePlus
T2370 Phosphorylation PhosphoSitePlus
Y2433 Phosphorylation PhosphoSitePlus
Y2614 Phosphorylation PhosphoSitePlus
T3058 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S295 I295 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
T982 A982 Biomuta DOID:3571 / liver cancer [ tcga ]
T1291 M1291 Biomuta DOID:1612 / breast cancer [ tcga ]
T1303 M1303 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
T1319 A1319 Biomuta DOID:263 / kidney cancer [ cosmic ]
T1319 N1319 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1525 F1525 Biomuta DOID:4159 / skin cancer [ icgc ]
S1804 N1804 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
S2047 F2047 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
Y2614 H2614 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]