iPTMnet Report for Q5SYE7 (NHSL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5SYE7 / NHSL1_HUMAN
Protein Name NHS-like protein 1
Gene Name Name: NHSL1
Synonyms:C6orf63,KIAA1357;
Organism Homo sapiens (Human)

PRO ID PR:Q5SYE7
DAG View
PRO Name NHS-like protein 1 (human)
Definition An NHS-like protein 1 that is encoded in the genome of human.
Short Label hNHSL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5SYE7 (NHSL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
Y151 Phosphorylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
T180 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus   UniProt 23186163
T241 Phosphorylation PhosphoSitePlus
R319 Methylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S388 Phosphorylation PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus
S470 Phosphorylation PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus
Y559 Phosphorylation PhosphoSitePlus
S639 Phosphorylation PhosphoSitePlus
S662 Phosphorylation PhosphoSitePlus
S668 Phosphorylation PhosphoSitePlus
S684 Phosphorylation PhosphoSitePlus
S723 Phosphorylation PhosphoSitePlus
S725 Phosphorylation PhosphoSitePlus
S727 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PhosphoSitePlus
S740 Phosphorylation PhosphoSitePlus
S742 Phosphorylation PhosphoSitePlus
S762 Phosphorylation PhosphoSitePlus
S771 Phosphorylation PhosphoSitePlus
T773 Phosphorylation PhosphoSitePlus
S842 Phosphorylation PhosphoSitePlus
S877 Phosphorylation PhosphoSitePlus
S895 Phosphorylation PhosphoSitePlus
S898 Phosphorylation PhosphoSitePlus
S901 Phosphorylation PhosphoSitePlus
S910 Phosphorylation PhosphoSitePlus
S911 Phosphorylation PhosphoSitePlus
S914 Phosphorylation PhosphoSitePlus
T915 Phosphorylation PhosphoSitePlus
S918 Phosphorylation PhosphoSitePlus
S930 Phosphorylation PhosphoSitePlus
S941 Phosphorylation PhosphoSitePlus
S1089 Phosphorylation PhosphoSitePlus
T1106 Phosphorylation PhosphoSitePlus
Y1112 Phosphorylation PhosphoSitePlus
T1144 Phosphorylation PhosphoSitePlus
S1165 Phosphorylation PhosphoSitePlus
S1167 Phosphorylation PhosphoSitePlus   UniProt 18669648
S1181 Phosphorylation PhosphoSitePlus
S1183 Phosphorylation PhosphoSitePlus
T1184 Phosphorylation PhosphoSitePlus
T1185 Phosphorylation PhosphoSitePlus
S1190 Phosphorylation PhosphoSitePlus
S1191 Phosphorylation PhosphoSitePlus
S1193 Phosphorylation PhosphoSitePlus
S1233 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1235 Phosphorylation PhosphoSitePlus
T1236 Phosphorylation PhosphoSitePlus
S1274 Phosphorylation PhosphoSitePlus
S1276 Phosphorylation PhosphoSitePlus
S1278 Phosphorylation PhosphoSitePlus
S1292 Phosphorylation PhosphoSitePlus
T1350 Phosphorylation PhosphoSitePlus
T1356 O-Glycosylation GlyGen 30379171, 31492838
T1357 O-Glycosylation GlyGen 30379171, 31492838
S1367 O-Glycosylation GlyGen 30379171, 31492838
S1367 Phosphorylation PhosphoSitePlus
S1377 Phosphorylation PhosphoSitePlus
S1382 Phosphorylation PhosphoSitePlus
S1386 Phosphorylation PhosphoSitePlus   UniProt 18669648, 21406692, 24275569
S1388 Phosphorylation PhosphoSitePlus   UniProt 18669648, 21406692, 24275569
T1392 Phosphorylation PhosphoSitePlus   UniProt 18669648, 24275569
T1394 Phosphorylation PhosphoSitePlus
S1402 Phosphorylation PhosphoSitePlus
S1408 Phosphorylation PhosphoSitePlus
K1415 Methylation PhosphoSitePlus
S1416 Phosphorylation PhosphoSitePlus
K1424 Methylation PhosphoSitePlus
S1441 Phosphorylation PhosphoSitePlus
S1458 Phosphorylation PhosphoSitePlus
S1461 Phosphorylation PhosphoSitePlus
S1467 Phosphorylation PhosphoSitePlus
S1469 Phosphorylation PhosphoSitePlus
S1470 Phosphorylation PhosphoSitePlus
S1472 Phosphorylation PhosphoSitePlus
S1474 Phosphorylation PhosphoSitePlus
S1495 Phosphorylation PhosphoSitePlus
S1497 Phosphorylation PhosphoSitePlus
R1500 Methylation PhosphoSitePlus
T1506 Phosphorylation PhosphoSitePlus
S1524 Phosphorylation PhosphoSitePlus
S1530 Phosphorylation PhosphoSitePlus
S1555 Phosphorylation PhosphoSitePlus
S1599 Phosphorylation PhosphoSitePlus
S1605 Phosphorylation PhosphoSitePlus
S1607 Phosphorylation PhosphoSitePlus
S1610 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K19 Acetylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
Y193 Phosphorylation PhosphoSitePlus
T194 Phosphorylation PhosphoSitePlus
T196 Phosphorylation PhosphoSitePlus
T209 Phosphorylation PhosphoSitePlus
T211 Phosphorylation PhosphoSitePlus
Y236 Phosphorylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
S242 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S174 F174 Biomuta DOID:4159 / skin cancer [ cosmic ]
R319 C319 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S388 A388 Biomuta DOID:263 / kidney cancer [ cosmic ]
S491 F491 Biomuta DOID:4159 / skin cancer [ cosmic ]
S740 F740 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S842 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S1167 I1167 Biomuta DOID:3571 / liver cancer [ cosmic ]
T1236 M1236 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ]
S1274 Y1274 Biomuta DOID:363 / uterine cancer [ icgc ]
S1278 N1278 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T1357 P1357 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T1394 N1394 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1424 N1424 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1474 R1474 Biomuta DOID:2021 / placenta cancer [ cosmic ]
T1506 M1506 Biomuta DOID:363 / uterine cancer [ icgc ]
S1530 L1530 Biomuta DOID:9256 / colorectal cancer [ cosmic ]