iPTMnet Report for Q5MIZ7 (PPP4R3B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5MIZ7 / P4R3B_HUMAN
Protein Name Serine/threonine-protein phosphatase 4 regulatory subunit 3B
Gene Name Name: PPP4R3B
Synonyms:KIAA1387,PP4R3B,SMEK2;
Organism Homo sapiens (Human)

PRO ID PR:Q5MIZ7
DAG View
PRO Name serine/threonine-protein phosphatase 4 regulatory subunit 3B (human)
Definition A serine/threonine-protein phosphatase 4 regulatory subunit 3B that is encoded in the genome of human.
Short Label hPPP4R3B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5MIZ7 (PPP4R3B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K9 Ubiquitination PhosphoSitePlus
R17 Methylation PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus   UniProt 21406692
C137 Methylation IEDB 31844290
S155 Phosphorylation PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
Y171 Phosphorylation PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
C341 Methylation IEDB 31844290
T457 Phosphorylation PhosphoSitePlus
T482 Phosphorylation PhosphoSitePlus
S483 Phosphorylation PhosphoSitePlus
K489 Ubiquitination PhosphoSitePlus
K601 Ubiquitination PhosphoSitePlus
K611 Ubiquitination PhosphoSitePlus
K673 Acetylation PhosphoSitePlus
K676 Acetylation PhosphoSitePlus
T677 Phosphorylation PhosphoSitePlus
Y679 Phosphorylation PhosphoSitePlus
S695 Phosphorylation PhosphoSitePlus   UniProt 23186163
K726 Sumoylation PhosphoSitePlus
T751 Phosphorylation IEDB 35494241
K755 Acetylation PhosphoSitePlus
T767 O-Glycosylation GlyGen 34725712, 35254053
S768 Phosphorylation PhosphoSitePlus
S777 Phosphorylation PhosphoSitePlus
S779 Phosphorylation PhosphoSitePlus
Y827 Phosphorylation PhosphoSitePlus
S840 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243
Site PTM Type PTM Enzyme Score Source PMID
S117 Phosphorylation HPRD 19664994, 18452278
S495 Phosphorylation PhosphoSitePlus
T500 Phosphorylation PhosphoSitePlus
Y594 Phosphorylation HPRD 17924679
S683 Phosphorylation HPRD 20068231
S754 Phosphorylation HPRD 18452278
S755 Phosphorylation HPRD 19413330, 16964243


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K9 N9 Biomuta DOID:4159 / skin cancer [ cosmic ]
K96 N96 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S483 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S495 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K601 N601 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S683 T683 Biomuta DOID:363 / uterine cancer [ cosmic ]
K726 N726 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S754 L754 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T767 A767 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S768 T768 Biomuta DOID:363 / uterine cancer [ cosmic ]