iPTMnet Report for Q5JXC2 (MIIP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5JXC2 / MIIP_HUMAN
Protein Name Migration and invasion-inhibitory protein
Gene Name Name: MIIP
Synonyms:IIP45;
Organism Homo sapiens (Human)

PRO ID PR:Q5JXC2
DAG View
PRO Name migration and invasion-inhibitory protein (human)
Definition An invasion-inhibitory protein 45 that is encoded in the genome of human.
Short Label hMIIP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5JXC2 (MIIP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S40 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
T54 Phosphorylation PhosphoSitePlus
T57 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
S113 Phosphorylation IEDB   PhosphoSitePlus 27869121
T141 Phosphorylation PhosphoSitePlus   UniProt 23186163
T158 Phosphorylation RLIMS-P 29038521
K210 Ubiquitination PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
T258 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 29038521, 23186163, 21406692
S352 Phosphorylation PhosphoSitePlus
T354 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
T370 Phosphorylation PhosphoSitePlus
T372 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S303 Phosphorylation HPRD 19651622


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q5JXC2 (MIIP) S303 Q04206 (RELA) unknown eFIP 29038521


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S61 F61 Biomuta DOID:4159 / skin cancer [ cosmic ]
K99 N99 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
Y241 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
T354 I354 Biomuta DOID:4159 / skin cancer [ cosmic ]