iPTMnet Report for Q5JVG8 (ZNF506)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5JVG8 / ZN506_HUMAN
Protein Name Zinc finger protein 506
Gene Name Name: ZNF506
Organism Homo sapiens (Human)

PRO ID PR:Q5JVG8
DAG View
PRO Name zinc finger protein 506 (human)
Definition A zinc finger protein 506 that is encoded in the genome of human.
Short Label hZNF506
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5JVG8 (ZNF506) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S48 Phosphorylation PhosphoSitePlus
T54 Phosphorylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
T140 Phosphorylation RLIMS-P 30013081
C147 Methylation IEDB 31844290
K221 Ubiquitination PhosphoSitePlus
T224 Phosphorylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K230 Sumoylation PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
T252 Phosphorylation PhosphoSitePlus
K255 Sumoylation PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
T280 Phosphorylation PhosphoSitePlus
T308 Phosphorylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K314 Acetylation PhosphoSitePlus
K314 Sumoylation PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
K370 Sumoylation PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
T392 Phosphorylation PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
K398 Acetylation PhosphoSitePlus
K398 Sumoylation PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q5JVG8 (ZNF506) T140 Q14676 (MDC1) unknown eFIP 30013081


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K221 R221 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
K221 I221 Biomuta DOID:4606 / bile duct cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
T224 N224 Biomuta DOID:363 / uterine cancer [ icgc ]
T280 N280 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K314 I314 Biomuta DOID:363 / uterine cancer [ icgc ]
Y341 H341 Biomuta DOID:1319 / brain cancer [ cosmic ]
K388 N388 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]