Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5JU85 / IQEC2_HUMAN
Protein Name IQ motif and SEC7 domain-containing protein 2
Gene Name Name: IQSEC2
Synonyms:KIAA0522;
Organism Homo sapiens (Human)

PRO ID PR:Q5JU85
DAG View
PRO Name IQ motif and SEC7 domain-containing protein 2 (human)
Definition An IQ motif and SEC7 domain-containing protein 2 that is encoded in the genome of human.
Short Label hIQSEC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5JU85 (IQSEC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation PhosphoSitePlus
Y89 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
Y139 Phosphorylation PhosphoSitePlus
Y188 Phosphorylation PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
R207 Methylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
S344 Phosphorylation UniProt 23186163
S393 Phosphorylation UniProt 21406692, 23186163
K399 Acetylation PhosphoSitePlus
S412 Phosphorylation UniProt 23186163
S1107 Phosphorylation UniProt 23186163
S1143 Phosphorylation UniProt 23186163
S1148 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T231 Phosphorylation PhosphoSitePlus
T244 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S918 Phosphorylation HPRD 18452278
Y924 Phosphorylation HPRD 18452278
S938 Phosphorylation HPRD   PhosphoSitePlus 19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S105 I105 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
R207 C207 Biomuta DOID:1909 / melanoma [ cosmic ]
R207 S207 Biomuta DOID:3571 / liver cancer [ icgc ]