Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5JSZ5 / PRC2B_HUMAN
Protein Name Protein PRRC2B
Gene Name Name: PRRC2B
Synonyms:BAT2L,BAT2L1,KIAA0515;
Organism Homo sapiens (Human)

PRO ID PR:Q5JSZ5
DAG View
PRO Name protein PRRC2B (human)
Definition A protein BAT2-like that is encoded in the genome of human.
Short Label hPRRC2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5JSZ5 (PRRC2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y18 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
Y27 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
R56 Methylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
R163 Methylation PhosphoSitePlus
S166 Phosphorylation O14757 (CHEK1) phospho.ELM   PhosphoSitePlus   UniProt 16964243, 18669648, 21851590, ...19690332, 20068231
S168 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 18669648, ...20068231, 17081983
T174 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
Y195 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
S224 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S226 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
T228 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S244 Phosphorylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
R300 Methylation PhosphoSitePlus
R313 Methylation PhosphoSitePlus
S388 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18318008, ...18669648, 19690332, 20068231
S406 Phosphorylation PhosphoSitePlus
S416 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
S418 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
Y467 Phosphorylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus   UniProt 23186163
K528 Ubiquitination PhosphoSitePlus
S556 O-Glycosylation GlyGen 23301498, 28314751, 30059200, ...29351928, 22661428, 29485866, 32119511, 28657654, 29237092
S556 Phosphorylation PhosphoSitePlus   UniProt 23186163
S558 Phosphorylation PhosphoSitePlus
S563 Phosphorylation PhosphoSitePlus
S575 Phosphorylation PhosphoSitePlus
S595 Phosphorylation PhosphoSitePlus
S613 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
Y641 Phosphorylation PhosphoSitePlus
R673 Methylation PhosphoSitePlus
R684 Methylation PhosphoSitePlus
T686 Phosphorylation PhosphoSitePlus
T736 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S740 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S745 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
Y749 Phosphorylation PhosphoSitePlus
K755 Ubiquitination PhosphoSitePlus
Y757 Phosphorylation PhosphoSitePlus
S764 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S765 Phosphorylation PhosphoSitePlus   UniProt 23186163
S778 Phosphorylation PhosphoSitePlus
S779 Phosphorylation PhosphoSitePlus
S783 Phosphorylation PhosphoSitePlus
R786 Methylation PhosphoSitePlus
Y804 Phosphorylation PhosphoSitePlus
K810 Ubiquitination PhosphoSitePlus
S853 Phosphorylation PhosphoSitePlus
S870 Phosphorylation PhosphoSitePlus
S874 Phosphorylation PhosphoSitePlus
S907 Phosphorylation PhosphoSitePlus
S913 Phosphorylation PhosphoSitePlus
S914 Phosphorylation PhosphoSitePlus
T919 Phosphorylation PhosphoSitePlus
S925 Phosphorylation PhosphoSitePlus
T936 Phosphorylation PhosphoSitePlus
S939 Phosphorylation PhosphoSitePlus
K963 Sumoylation PhosphoSitePlus
S980 Phosphorylation PhosphoSitePlus
K1006 Ubiquitination PhosphoSitePlus
R1077 Methylation PhosphoSitePlus
R1079 Methylation PhosphoSitePlus
R1097 Methylation PhosphoSitePlus
Y1100 Phosphorylation PhosphoSitePlus
S1102 Phosphorylation PhosphoSitePlus
R1108 Methylation PhosphoSitePlus
R1110 Methylation PhosphoSitePlus
R1113 Methylation PhosphoSitePlus
S1132 Phosphorylation PhosphoSitePlus   UniProt 18669648
T1134 Phosphorylation PhosphoSitePlus
S1136 Phosphorylation PhosphoSitePlus
S1139 Phosphorylation PhosphoSitePlus
Y1141 Phosphorylation PhosphoSitePlus
S1153 Phosphorylation PhosphoSitePlus
S1160 Phosphorylation PhosphoSitePlus
S1185 Phosphorylation PhosphoSitePlus
S1224 Phosphorylation PhosphoSitePlus
K1230 Ubiquitination PhosphoSitePlus
S1231 Phosphorylation PhosphoSitePlus   UniProt 18669648
S1234 Phosphorylation PhosphoSitePlus
R1297 Methylation PhosphoSitePlus
S1358 Phosphorylation PhosphoSitePlus
T1376 Phosphorylation PhosphoSitePlus
S1384 Phosphorylation PhosphoSitePlus
S1395 Phosphorylation PhosphoSitePlus
S1399 Phosphorylation PhosphoSitePlus
S1420 Phosphorylation PhosphoSitePlus
S1422 Phosphorylation PhosphoSitePlus
S1423 Phosphorylation PhosphoSitePlus
S1432 Phosphorylation PhosphoSitePlus
T1452 Phosphorylation PhosphoSitePlus
S1453 Phosphorylation PhosphoSitePlus
T1463 Phosphorylation PhosphoSitePlus
S1470 Phosphorylation PhosphoSitePlus   UniProt 18669648
S1480 Phosphorylation PhosphoSitePlus
S1483 Phosphorylation PhosphoSitePlus
S1486 Phosphorylation PhosphoSitePlus
S1489 Phosphorylation PhosphoSitePlus
Y1491 Phosphorylation PhosphoSitePlus
S1507 Phosphorylation PhosphoSitePlus   UniProt 20068231
S1595 Phosphorylation PhosphoSitePlus
K1647 Ubiquitination PhosphoSitePlus
S1666 Phosphorylation PhosphoSitePlus
S1667 Phosphorylation PhosphoSitePlus
S1671 Phosphorylation PhosphoSitePlus
S1676 Phosphorylation PhosphoSitePlus
S1679 Phosphorylation PhosphoSitePlus
S1687 Phosphorylation PhosphoSitePlus
S1691 Phosphorylation PhosphoSitePlus
Y1693 Phosphorylation PhosphoSitePlus
T1695 Phosphorylation PhosphoSitePlus
S1702 Phosphorylation PhosphoSitePlus
S1747 Phosphorylation PhosphoSitePlus
S1754 Phosphorylation PhosphoSitePlus   UniProt 17081983
S1789 Phosphorylation PhosphoSitePlus
S1801 O-Glycosylation GlyGen 23301498, 28314751, 30059200, ...29351928, 22661428, 29485866, 32119511, 28657654, 29237092
S1803 Phosphorylation PhosphoSitePlus
S1808 Phosphorylation PhosphoSitePlus
S1826 Phosphorylation PhosphoSitePlus
S1843 Phosphorylation PhosphoSitePlus   UniProt 18669648
S1846 Phosphorylation PhosphoSitePlus
R1976 Methylation PhosphoSitePlus
S1982 O-Glycosylation GlyGen 23301498, 28314751, 30059200, ...29351928, 22661428, 29485866, 32119511, 28657654, 29237092
S1984 O-Glycosylation GlyGen 23301498, 28314751, 30059200, ...29351928, 22661428, 29485866, 32119511, 28657654, 29237092
S1984 Phosphorylation PhosphoSitePlus
S1989 O-Glycosylation GlyGen 23301498, 28314751, 30059200, ...29351928, 22661428, 29485866, 32119511, 28657654, 29237092
S1990 O-Glycosylation GlyGen 23301498, 28314751, 30059200, ...29351928, 22661428, 29485866, 32119511, 28657654, 29237092
S2003 Phosphorylation PhosphoSitePlus
S2005 Phosphorylation PhosphoSitePlus
S2105 Phosphorylation PhosphoSitePlus
R2110 Methylation PhosphoSitePlus
S2153 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S166 Phosphorylation HPRD 18669648, 16964243, 20068231
S168 Phosphorylation HPRD 18691976, 18669648, 16964243, ...20068231, 19664995
S224 Phosphorylation HPRD 18669648, 20068231
T225 Phosphorylation HPRD 19664995, 20068231
S226 Phosphorylation HPRD 19651622, 18669648, 19664995, ...20068231, 18452278
T228 Phosphorylation HPRD 18669648
S388 Phosphorylation HPRD 18212344, 19664995, 18452278, ...19651622, 18669648, 20166139, 20068231
S416 Phosphorylation HPRD 18669648, 20068231
S480 Phosphorylation HPRD 18212344, 20068231
S556 Phosphorylation HPRD 19413330
S563 Phosphorylation HPRD 19651622, 20068231
S613 Phosphorylation HPRD 19007248, 20068231
T686 Phosphorylation HPRD 20068231
T736 Phosphorylation HPRD 18669648
S740 Phosphorylation HPRD 19413330, 18669648, 20068231
S745 Phosphorylation HPRD 19413330, 18669648, 20068231
Y757 Phosphorylation HPRD 20068231
S764 Phosphorylation HPRD 18669648
T767 Phosphorylation HPRD 20068231
S1132 Phosphorylation HPRD 19651622, 18669648
T1134 Phosphorylation HPRD 18669648
S1136 Phosphorylation HPRD 19651622, 18669648
S1231 Phosphorylation HPRD 18669648, 20068231
S1235 Phosphorylation HPRD 18669648
S1470 Phosphorylation HPRD 18669648
Y1491 Phosphorylation HPRD 18669648
S1507 Phosphorylation HPRD 20068231
S1691 Phosphorylation HPRD 18669648
S1808 Phosphorylation HPRD 20068231
S1843 Phosphorylation HPRD 18669648, 20068231
S2169 Phosphorylation HPRD 20068231
Y2182 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S31 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
T225 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
S563 Phosphorylation PhosphoSitePlus
S613 Phosphorylation PhosphoSitePlus
Y641 Phosphorylation PhosphoSitePlus
S740 Phosphorylation PhosphoSitePlus
S745 Phosphorylation PhosphoSitePlus
S776 Phosphorylation PhosphoSitePlus
S786 Phosphorylation PhosphoSitePlus
S790 Phosphorylation PhosphoSitePlus
S795 Phosphorylation PhosphoSitePlus
Y797 Phosphorylation PhosphoSitePlus
S813 Phosphorylation PhosphoSitePlus
K816 Ubiquitination PhosphoSitePlus
S996 Phosphorylation PhosphoSitePlus
S997 Phosphorylation PhosphoSitePlus
T1001 Phosphorylation PhosphoSitePlus
S1060 Phosphorylation PhosphoSitePlus
S1114 Phosphorylation PhosphoSitePlus
S1149 Phosphorylation PhosphoSitePlus
Y1488 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y18 * Biomuta DOID:2531 / hematologic cancer [ icgc ]
S19 L19 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
R56 H56 Biomuta DOID:9256 / colorectal cancer [ icgc ]
R56 C56 Biomuta DOID:11934 / head and neck cancer [ tcga ]
R163 G163 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S224 R224 Biomuta DOID:3070 / malignant glioma [ tcga ]
S288 L288 Biomuta DOID:2394 / ovarian cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
S595 Y595 Biomuta DOID:2994 / germ cell cancer [ tcga ]
R684 H684 Biomuta DOID:363 / uterine cancer [ tcga ]
T686 M686 Biomuta DOID:1793 / pancreatic cancer [ icgc, tcga ] DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, tcga ]
S783 P783 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
R786 K786 Biomuta DOID:0070003 / blastoma [ cosmic ]
S907 N907 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
T936 S936 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S939 L939 Biomuta DOID:1909 / melanoma [ cosmic ]
K963 M963 Biomuta DOID:0070003 / blastoma [ cosmic ]
K963 R963 Biomuta DOID:1909 / melanoma [ cosmic ]
R1077 C1077 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
R1097 C1097 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R1097 H1097 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
R1108 C1108 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
R1113 * Biomuta DOID:10534 / stomach cancer [ icgc ]
S1136 I1136 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S1160 L1160 Biomuta DOID:363 / uterine cancer [ tcga ]
S1432 R1432 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
T1463 A1463 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S1480 C1480 Biomuta DOID:1324 / lung cancer [ tcga ]
S1595 F1595 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S1666 N1666 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S1676 I1676 Biomuta DOID:3571 / liver cancer [ tcga ]
S1679 Y1679 Biomuta DOID:3571 / liver cancer [ tcga ]
S1687 L1687 Biomuta DOID:1324 / lung cancer [ cosmic ]
S2105 F2105 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:1909 / melanoma [ icgc, tcga ]