iPTMnet Report for Q5JSJ4 (INTS6L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5JSJ4 / INT6L_HUMAN
Protein Name Integrator complex subunit 6-like
Gene Name Name: INTS6L
Synonyms:DDX26B;
Organism Homo sapiens (Human)

PRO ID PR:Q5JSJ4
DAG View
PRO Name integrator complex subunit 6-like (human)
Definition An integrator complex subunit 6-like that is encoded in the genome of human.
Short Label hINTS6L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5JSJ4 (INTS6L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y24 Phosphorylation PhosphoSitePlus
Y50 Phosphorylation PhosphoSitePlus
Y60 Phosphorylation PhosphoSitePlus
T238 Phosphorylation PhosphoSitePlus
Y426 Phosphorylation PhosphoSitePlus
Y427 Phosphorylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
Y513 Phosphorylation PhosphoSitePlus
T525 Phosphorylation PhosphoSitePlus
S566 Phosphorylation PhosphoSitePlus
T581 Phosphorylation PhosphoSitePlus
S617 Phosphorylation PhosphoSitePlus   UniProt 23186163
S626 Phosphorylation PhosphoSitePlus
S628 Phosphorylation PhosphoSitePlus
T688 Phosphorylation PhosphoSitePlus
Y835 Phosphorylation PhosphoSitePlus
K838 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y24 Phosphorylation HPRD 18452278
Y835 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K467 T467 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K467 N467 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T581 I581 Biomuta DOID:363 / uterine cancer [ icgc ]
T581 N581 Biomuta DOID:363 / uterine cancer [ icgc ]
S617 N617 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K838 N838 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]