iPTMnet Report for Q5JSH3 (WDR44)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5JSH3 / WDR44_HUMAN
Protein Name WD repeat-containing protein 44
Gene Name Name: WDR44
Synonyms:RPH11;
Organism Homo sapiens (Human)

PRO ID PR:Q5JSH3
DAG View
PRO Name WD repeat-containing protein 44 (human)
Definition A WD repeat-containing protein 44 that is encoded in the genome of human.
Short Label hWDR44
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5JSH3 (WDR44) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 20068231
S3 Phosphorylation PhosphoSitePlus   UniProt 20068231
S5 Phosphorylation PhosphoSitePlus
Y11 Phosphorylation UniProt 17081983
S27 Phosphorylation PhosphoSitePlus   UniProt 20068231, 17081983, 24275569
S34 Phosphorylation PhosphoSitePlus
T35 Phosphorylation PhosphoSitePlus
S50 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 17287340, 20068231
S66 Phosphorylation PhosphoSitePlus   UniProt 23186163
S71 Phosphorylation PhosphoSitePlus   UniProt 23186163
S81 Phosphorylation PhosphoSitePlus   UniProt 23186163
S84 Phosphorylation PhosphoSitePlus
K87 Acetylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
S96 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 18220336, ...15302935, 18669648, 24275569, 19690332, 20068231
S126 Phosphorylation PhosphoSitePlus   UniProt 23186163
T129 Phosphorylation PhosphoSitePlus
T158 Phosphorylation PhosphoSitePlus   UniProt 23186163
S161 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S162 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T163 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 15302935
T171 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
T200 Phosphorylation phospho.ELM 18669648
K201 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
T219 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S227 Phosphorylation PhosphoSitePlus
P243 Methylation IEDB 29786170
K261 Ubiquitination PhosphoSitePlus
S262 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 17287340, 20068231
T268 Phosphorylation PhosphoSitePlus
T271 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340
S290 Phosphorylation PhosphoSitePlus
S342 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 31204173, 18669648, 31665227, ...20068231
S344 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 17081983, 18669648, ...31204173, 30784271, 31665227
T349 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S397 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S403 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 24275569, 19690332, 20068231
S411 Phosphorylation PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
T426 Phosphorylation PhosphoSitePlus
K434 Acetylation PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
K437 Acetylation PhosphoSitePlus
K440 Ubiquitination PhosphoSitePlus
Y446 Phosphorylation PhosphoSitePlus
S470 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S471 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S472 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
Y479 Phosphorylation PhosphoSitePlus
T480 Phosphorylation PhosphoSitePlus
K486 Ubiquitination PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
Y495 Phosphorylation PhosphoSitePlus
K518 Ubiquitination PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
T556 Phosphorylation PhosphoSitePlus
S561 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17525332, ...18669648, 24275569
S563 Phosphorylation PhosphoSitePlus
S565 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18669648, 17525332
S568 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332, 18669648
S571 Phosphorylation PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus
S582 Phosphorylation PhosphoSitePlus
T584 Phosphorylation PhosphoSitePlus
S614 Phosphorylation PhosphoSitePlus
K681 Ubiquitination PhosphoSitePlus
T696 Phosphorylation PhosphoSitePlus
K744 Ubiquitination PhosphoSitePlus
K756 Ubiquitination PhosphoSitePlus
K779 Acetylation PhosphoSitePlus
K781 Acetylation PhosphoSitePlus
K781 Ubiquitination PhosphoSitePlus
Y783 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
T799 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
Y800 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S803 Phosphorylation PhosphoSitePlus
Y809 Phosphorylation PhosphoSitePlus
K870 Ubiquitination PhosphoSitePlus
S871 Phosphorylation PhosphoSitePlus
T880 Phosphorylation PhosphoSitePlus
S882 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation HPRD 20068231
S5 Phosphorylation HPRD 19413330, 17081983, 20068231
T7 Phosphorylation HPRD 17081983, 20068231
Y11 Phosphorylation HPRD 17081983
S27 Phosphorylation HPRD 17081983, 20068231
S50 Phosphorylation HPRD 19413330, 17287340, 18767875, ...19664994, 19664995, 18452278, 19651622, 18669648, 20058876, 20166139, 19415658, 20068231
S81 Phosphorylation HPRD 20068231
S90 Phosphorylation HPRD 19413330
S96 Phosphorylation HPRD 19413330, 16964243, 18767875, ...19664994, 19664995, 15302935, 18669648, 19415658, 20068231
T158 Phosphorylation HPRD 19413330, 19415658
S161 Phosphorylation HPRD 19413330, 18669648, 20068231
S162 Phosphorylation HPRD 19413330, 18669648, 20068231, ...18452278
T163 Phosphorylation HPRD 19413330, 18669648, 20058876
T200 Phosphorylation HPRD 18669648
T219 Phosphorylation HPRD 18669648, 20058876, 20068231
S262 Phosphorylation HPRD 17287340, 18767875, 19664994, ...18452278, 19651622, 18669648, 20068231
T271 Phosphorylation HPRD 17287340
S300 Phosphorylation HPRD 20068231
S308 Phosphorylation HPRD 20068231
T310 Phosphorylation HPRD 20068231
S342 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S344 Phosphorylation HPRD 18669648, 20068231, 18452278
T349 Phosphorylation HPRD 19651622, 18767875, 18669648, ...20068231
T392 Phosphorylation HPRD 20230923
S397 Phosphorylation HPRD 18669648, 20230923
S403 Phosphorylation HPRD 19413330, 20058876, 20230923, ...18767875, 19664994, 18452278, 19651622, 18510355, 18669648, 20166139, 19415658, 20068231
T426 Phosphorylation HPRD 18077418
S456 Phosphorylation HPRD 20068231
T464 Phosphorylation HPRD 19651622, 20068231
S470 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231
S471 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231
S472 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231
Y479 Phosphorylation HPRD 20068231
S561 Phosphorylation HPRD 19413330, 18691976, 17525332, ...20058876, 19664994, 19651622, 18669648, 20068231
S563 Phosphorylation HPRD 19413330, 20068231
S565 Phosphorylation HPRD 19413330, 19651622, 17525332, ...18669648
S568 Phosphorylation HPRD 19413330, 19651622, 17525332, ...18669648, 20068231
S570 Phosphorylation HPRD 20068231
S571 Phosphorylation HPRD 19651622, 20068231
S614 Phosphorylation HPRD 19664995
Y783 Phosphorylation HPRD 17287340
T799 Phosphorylation HPRD 17287340
Y800 Phosphorylation HPRD 17287340


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S3 W3 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S3 L3 Biomuta DOID:363 / uterine cancer [ icgc ]
S5 R5 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S27 P27 Biomuta DOID:363 / uterine cancer [ icgc ]
S84 F84 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K87 E87 Biomuta DOID:4159 / skin cancer [ cosmic ]
S96 R96 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S126 T126 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S126 N126 Biomuta DOID:363 / uterine cancer [ icgc ]
T163 S163 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
P243 L243 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
K261 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S290 R290 Biomuta DOID:1324 / lung cancer [ cosmic ]
S290 G290 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S300 Y300 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S411 F411 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S435 * Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K437 N437 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S456 T456 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T464 I464 Biomuta DOID:363 / uterine cancer [ icgc ]
S471 L471 Biomuta DOID:363 / uterine cancer [ icgc ]
S472 G472 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y479 H479 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y479 C479 Biomuta DOID:1319 / brain cancer [ cosmic ]
T480 I480 Biomuta DOID:3565 / meningioma [ cosmic ]
K518 T518 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S528 L528 Biomuta DOID:1319 / brain cancer [ cosmic ]
S574 L574 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S614 L614 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
K681 N681 Biomuta DOID:363 / uterine cancer [ icgc ]
K756 T756 Biomuta DOID:363 / uterine cancer [ icgc ]
K870 I870 Biomuta DOID:2531 / hematologic cancer [ cosmic ]