iPTMnet Report for Q5JRA6 (MIA3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5JRA6 / TGO1_HUMAN
Protein Name Transport and Golgi organization protein 1 homolog precursor
Gene Name Name: MIA3
Synonyms:KIAA0268;ORFNames:UNQ6077/PRO20088;
Organism Homo sapiens (Human)

PRO ID PR:Q5JRA6
DAG View
PRO Name transport and Golgi organization protein 1 homolog (human)
Definition A transport and Golgi organization protein 1 homolog that is encoded in the genome of human.
Short Label hMIA3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5JRA6 (MIA3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S33 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
T57 Phosphorylation PhosphoSitePlus
Y73 Phosphorylation PhosphoSitePlus
T152 O-Glycosylation GlyGen 25813380
K156 Ubiquitination PhosphoSitePlus
T161 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S186 Phosphorylation PhosphoSitePlus
T206 O-Glycosylation GlyGen 25813380
S211 O-Glycosylation GlyGen 25813380
S215 O-Glycosylation GlyGen 25813380
S226 Phosphorylation UniProt 26091039
S229 Phosphorylation UniProt 26091039
N246 N-Glycosylation GlyGen 29741879
T248 Phosphorylation PhosphoSitePlus
N250 N-Glycosylation GlyGen 23090970, 29741879, 24190977
K278 Ubiquitination PhosphoSitePlus
S281 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T282 O-Glycosylation GlyGen 25813380
T282 Phosphorylation PhosphoSitePlus
S288 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T292 O-Glycosylation GlyGen 25813380
T293 O-Glycosylation GlyGen 25813380
T293 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T297 O-Glycosylation GlyGen 25813380
Y350 Phosphorylation PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
T392 O-Glycosylation GlyGen 25813380
S405 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S407 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S408 Phosphorylation PhosphoSitePlus
K451 Acetylation PhosphoSitePlus
T524 Phosphorylation PhosphoSitePlus
S579 O-Glycosylation GlyGen 33214551, 35138101, 30059200, ...29351928, 34019948, 29237092, 35254053, 22661428, 34105348
N589 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
S591 O-Glycosylation GlyGen 33214551, 35138101, 30059200, ...29351928, 34019948, 29237092, 35254053, 22661428, 34105348
S591 Phosphorylation PhosphoSitePlus
N602 N-Glycosylation GlyGen 24190977
T608 O-Glycosylation GlyGen 25813380
T666 O-Glycosylation GlyGen 25813380
S672 O-Glycosylation GlyGen 25813380
T711 O-Glycosylation GlyGen 30459171
S727 Phosphorylation PhosphoSitePlus   UniProt 24275569
K740 Ubiquitination PhosphoSitePlus
T768 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S788 Phosphorylation PhosphoSitePlus
T838 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T864 O-Glycosylation GlyGen 33214551, 35138101, 30059200, ...29351928, 34019948, 29237092, 35254053, 22661428, 34105348
S865 O-Glycosylation GlyGen 33214551, 35138101, 30059200, ...29351928, 34019948, 29237092, 35254053, 22661428, 34105348
S876 Phosphorylation PhosphoSitePlus   UniProt 24275569
S903 O-Glycosylation GlyGen 25813380
T907 O-Glycosylation GlyGen 25813380
T910 O-Glycosylation GlyGen 25813380
S911 O-Glycosylation GlyGen 25813380
Y969 Phosphorylation PhosphoSitePlus
T1040 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S1067 Phosphorylation PhosphoSitePlus   UniProt 24275569
T1083 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T1093 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380, 34105348
S1099 O-Glycosylation GlyGen   PhosphoSitePlus 33214551, 35138101, 25813380, ...30059200, 29351928, 34019948, 29237092, 23584533, 35254053, 22661428, 34105348
T1104 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T1115 O-Glycosylation GlyGen 30459171
K1158 Acetylation PhosphoSitePlus
S1159 Phosphorylation PhosphoSitePlus
T1163 Phosphorylation PhosphoSitePlus
Y1175 Phosphorylation PhosphoSitePlus
K1219 Ubiquitination PhosphoSitePlus
K1221 Ubiquitination PhosphoSitePlus
K1233 Ubiquitination PhosphoSitePlus
K1240 Ubiquitination PhosphoSitePlus
T1251 Phosphorylation PhosphoSitePlus
K1253 Ubiquitination PhosphoSitePlus
K1274 Ubiquitination PhosphoSitePlus
K1284 Ubiquitination PhosphoSitePlus
S1431 Phosphorylation PhosphoSitePlus
K1472 Ubiquitination PhosphoSitePlus
K1477 Ubiquitination PhosphoSitePlus
S1483 Phosphorylation PhosphoSitePlus
T1484 Phosphorylation PhosphoSitePlus
K1485 Ubiquitination PhosphoSitePlus
K1506 Ubiquitination PhosphoSitePlus
T1515 Phosphorylation PhosphoSitePlus
S1539 Phosphorylation PhosphoSitePlus
S1553 Phosphorylation PhosphoSitePlus
Y1569 Phosphorylation PhosphoSitePlus
K1597 Ubiquitination PhosphoSitePlus
S1666 Phosphorylation PhosphoSitePlus
S1670 Phosphorylation PhosphoSitePlus
S1673 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1678 Phosphorylation PhosphoSitePlus
T1682 Phosphorylation PhosphoSitePlus
S1691 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T1693 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1702 Phosphorylation PhosphoSitePlus
S1706 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K1723 Ubiquitination PhosphoSitePlus
S1725 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1727 Phosphorylation PhosphoSitePlus
T1733 Phosphorylation PhosphoSitePlus
T1735 Phosphorylation phospho.ELM 18669648
S1739 Phosphorylation PhosphoSitePlus
S1740 Phosphorylation PhosphoSitePlus
S1741 Phosphorylation PhosphoSitePlus
S1744 Phosphorylation PhosphoSitePlus
S1745 Phosphorylation PhosphoSitePlus   UniProt 21406692
R1809 Methylation PhosphoSitePlus
S1847 Phosphorylation PhosphoSitePlus
Y1853 Phosphorylation IEDB 32387766
R1859 Methylation PhosphoSitePlus
R1877 Methylation PhosphoSitePlus
S1906 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 26091039, 24275569
Site PTM Type PTM Enzyme Score Source PMID
S281 Phosphorylation HPRD 18669648, 20068231
S288 Phosphorylation HPRD 18669648
T293 Phosphorylation HPRD 18669648
S405 Phosphorylation HPRD 18669648
S407 Phosphorylation HPRD 18669648
S727 Phosphorylation HPRD 20166139, 19664994
S1673 Phosphorylation HPRD 18669648, 17081983
S1678 Phosphorylation HPRD 17081983
T1682 Phosphorylation HPRD 17081983
T1693 Phosphorylation HPRD 18669648, 17081983
S1725 Phosphorylation HPRD 18669648, 20068231
T1735 Phosphorylation HPRD 18669648
S1739 Phosphorylation HPRD 20068231
S1740 Phosphorylation HPRD 20068231
S1741 Phosphorylation HPRD 18452278
S1744 Phosphorylation HPRD 20068231
S1906 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y73 C73 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S186 L186 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T206 I206 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T206 S206 Biomuta DOID:363 / uterine cancer [ icgc ]
T206 A206 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S229 C229 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
N246 D246 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T297 I297 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y350 C350 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S408 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T608 M608 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T608 A608 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T666 P666 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T711 I711 Biomuta DOID:4159 / skin cancer [ cosmic ]
T907 N907 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T1083 I1083 Biomuta [ cosmic ]
T1093 I1093 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1159 L1159 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T1163 I1163 Biomuta DOID:363 / uterine cancer [ icgc ]
K1233 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K1284 E1284 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1483 P1483 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S1553 L1553 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y1569 S1569 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1693 I1693 Biomuta DOID:363 / uterine cancer [ icgc ]
S1702 N1702 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1706 * Biomuta DOID:1612 / breast cancer [ cosmic ]
T1735 I1735 Biomuta DOID:363 / uterine cancer [ icgc ]
R1809 H1809 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1847 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R1859 Q1859 Biomuta DOID:10283 / prostate cancer [ cosmic ]
R1877 S1877 Biomuta DOID:363 / uterine cancer [ icgc ]