iPTMnet Report for Q5JR12 (PPM1J)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5JR12 / PPM1J_HUMAN
Protein Name Protein phosphatase 1J
Gene Name Name: PPM1J
Synonyms:PPP2CZ;
Organism Homo sapiens (Human)

PRO ID PR:Q5JR12
DAG View
PRO Name protein phosphatase 1J (human)
Definition A protein phosphatase 1J that is encoded in the genome of human.
Short Label hPPM1J
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5JR12 (PPM1J) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus   UniProt 23186163
S76 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S93 Phosphorylation P45983 (MAPK8) , P45984 (MAPK9) , P53779 (MAPK10) neXtProt   Signor 18553930
S135 Phosphorylation PhosphoSitePlus
T201 Phosphorylation P45983 (MAPK8) neXtProt 18553930
T204 Phosphorylation P45983 (MAPK8) neXtProt   PhosphoSitePlus 18553930
Y273 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
K352 Acetylation PhosphoSitePlus
K353 Acetylation PhosphoSitePlus
Y458 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S76 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S280 N280 Biomuta DOID:363 / uterine cancer [ icgc ]
K313 R313 Biomuta DOID:4159 / skin cancer [ cosmic ]
K352 E352 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K353 T353 Biomuta DOID:363 / uterine cancer [ icgc ]