iPTMnet Report for Q5JPI9 (EEF1AKMT2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5JPI9 / EFMT2_HUMAN
Protein Name EEF1A lysine methyltransferase 2
Gene Name Name: EEF1AKMT2
Synonyms:C10orf138,METTL10;
Organism Homo sapiens (Human)

PRO ID PR:Q5JPI9
DAG View
PRO Name EEF1A lysine methyltransferase 2 (human)
Definition An EEF1A lysine methyltransferase 2 that is encoded in the genome of human.
Short Label hEEF1AKMT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5JPI9 (EEF1AKMT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 22814378
S17 Phosphorylation HPRD   PhosphoSitePlus 18669648
K19 Ubiquitination PhosphoSitePlus
S21 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 23186163
Y52 Phosphorylation PhosphoSitePlus
T55 Phosphorylation PhosphoSitePlus
S64 Phosphorylation IEDB   PhosphoSitePlus 35494241
S82 Phosphorylation PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
Y173 Phosphorylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
S178 Phosphorylation HPRD   PhosphoSitePlus 20068231
C257 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T55 A55 Biomuta DOID:3571 / liver cancer [ cosmic ]
K169 N169 Biomuta DOID:1612 / breast cancer [ cosmic ]
Y173 C173 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C257 F257 Biomuta DOID:1324 / lung cancer [ icgc ]