iPTMnet Report for Q5HYM0 (ZC3H12B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5HYM0 / ZC12B_HUMAN
Protein Name Probable ribonuclease ZC3H12B
Gene Name Name: ZC3H12B
Synonyms:CXorf32,MCPIP2;
Organism Homo sapiens (Human)

PRO ID PR:Q5HYM0
DAG View
PRO Name probable ribonuclease ZC3H12B (human)
Definition A probable ribonuclease ZC3H12B that is encoded in the genome of human.
Short Label hZC3H12B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5HYM0 (ZC3H12B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation PhosphoSitePlus
T9 Phosphorylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
S242 Phosphorylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
Y363 Phosphorylation PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
T424 Phosphorylation PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus
S529 Phosphorylation PhosphoSitePlus
S647 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T2 M2 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S17 F17 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S342 I342 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S418 G418 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S425 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]