iPTMnet Report for Q5HYK7 (SH3D19)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5HYK7 / SH319_HUMAN
Protein Name SH3 domain-containing protein 19
Gene Name Name: SH3D19
Organism Homo sapiens (Human)

PRO ID PR:Q5HYK7
DAG View
PRO Name SH3 domain-containing protein 19 (human)
Definition An SH3 domain-containing protein 19 that is encoded in the genome of human.
Short Label hSH3D19
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5HYK7 (SH3D19) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T6 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
T99 O-Glycosylation GlyGen 23301498, 35254053
K100 Ubiquitination PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
T137 Phosphorylation PhosphoSitePlus
K146 Methylation PhosphoSitePlus
K147 Methylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
T165 Phosphorylation PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
K180 Methylation PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
S181 Phosphorylation PhosphoSitePlus
T240 Phosphorylation PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
T257 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
S389 Phosphorylation PhosphoSitePlus
Y452 Phosphorylation PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
S696 Phosphorylation PhosphoSitePlus
K731 Ubiquitination PhosphoSitePlus
S762 Phosphorylation PhosphoSitePlus   UniProt 24275569
Site PTM Type PTM Enzyme Score Source PMID
S150 Phosphorylation HPRD 19413330, 18669648
Y452 Phosphorylation HPRD 17389395
S762 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S9 R9 Biomuta DOID:3571 / liver cancer [ cosmic ]
K45 E45 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S65 F65 Biomuta DOID:263 / kidney cancer [ icgc ]
S150 F150 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K180 M180 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T240 I240 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S378 I378 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S762 Y762 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]