iPTMnet Report for Q5HYI7 (MTX3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5HYI7 / MTX3_HUMAN
Protein Name Metaxin-3
Gene Name Name: MTX3
Organism Homo sapiens (Human)

PRO ID PR:Q5HYI7
DAG View
PRO Name metaxin-3 (human)
Definition A metaxin-3 that is encoded in the genome of human.
Short Label hMTX3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5HYI7 (MTX3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K38 Methylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K216 Acetylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
T255 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus   UniProt 23186163
T294 Phosphorylation PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus
S311 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K38 N38 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S244 N244 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T255 M255 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S306 F306 Biomuta DOID:4159 / skin cancer [ cosmic ]
S311 L311 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]