iPTMnet Report for Q5HY92 (FIGN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5HY92 / FIGN_HUMAN
Protein Name Fidgetin
Gene Name Name: FIGN
Organism Homo sapiens (Human)

PRO ID PR:Q5HY92
DAG View
PRO Name fidgetin (human)
Definition A fidgetin that is encoded in the genome of human.
Short Label hFIGN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5HY92 (FIGN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
R43 Methylation PhosphoSitePlus
S332 Phosphorylation PhosphoSitePlus
Y333 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
Y338 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
Y349 Phosphorylation PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
K377 Acetylation PhosphoSitePlus
S396 O-Glycosylation GlyGen 34019948, 35254053
T400 Phosphorylation PhosphoSitePlus   UniProt 23186163
S410 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
T423 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
K532 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S337 C337 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S343 Y343 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y349 H349 Biomuta DOID:3571 / liver cancer [ cosmic ]
S373 F373 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K377 E377 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
S396 R396 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T400 I400 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S410 L410 Biomuta [ cosmic ]