iPTMnet Report for Q5FWF5 (ESCO1)
Protein Information
| UniProt AC / UniProt ID | Q5FWF5 / ESCO1_HUMAN |
| Protein Name | N-acetyltransferase ESCO1 |
| Gene Name | Name: ESCO1 Synonyms:EFO1,KIAA1911; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q5FWF5 |
| PRO Name | N-acetyltransferase ESCO1 (human) |
| Definition | An N-acetyltransferase ESCO1 that is encoded in the genome of human. |
| Short Label | hESCO1 |
| Category | organism-gene |
DAG ViewQ5FWF5 (ESCO1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K9 | Acetylation | score1 | PhosphoSitePlus | |||
| S12 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| S13 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| K17 | Acetylation | score1 | PhosphoSitePlus | |||
| S24 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S31 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
| S55 | O-Glycosylation | score1 | GlyGen | 30379171, 29237092, 30620550 | ||
| K56 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T68 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S70 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T89 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S135 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S138 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S151 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T170 | O-Glycosylation | score1 | GlyGen | 30379171, 29237092, 30620550 | ||
| S184 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S186 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S200 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 20068231 | ||
| S218 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T268 | O-Glycosylation | score1 | GlyGen | 30379171, 29237092, 30620550 | ||
| S279 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S288 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K354 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K398 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K406 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S409 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S412 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
| S423 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S523 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T529 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S582 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T706 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S31 | Phosphorylation | score0 | HPRD | 17525332 | ||
| S135 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S138 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S151 | Phosphorylation | score0 | HPRD | 18452278 | ||
| S184 | Phosphorylation | score0 | HPRD | 18452278 | ||
| S186 | Phosphorylation | score0 | HPRD | 18452278 | ||
| S200 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S412 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S12 | Y12 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S31 | C31 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S31 | F31 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T68 | K68 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T68 | R68 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| S70 | P70 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T89 | N89 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S135 | L135 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] | |
| S200 | Y200 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K398 | T398 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S409 | F409 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
