iPTMnet Report for Q5BJE1 (CCDC178)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5BJE1 / CC178_HUMAN
Protein Name Coiled-coil domain-containing protein 178
Gene Name Name: CCDC178
Synonyms:C18orf34;
Organism Homo sapiens (Human)

PRO ID PR:Q5BJE1
DAG View
PRO Name coiled-coil domain-containing protein 178 (human)
Definition A coiled-coil domain-containing protein 178 that is encoded in the genome of human.
Short Label hCCDC178
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5BJE1 (CCDC178) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S44 Phosphorylation PhosphoSitePlus
Y50 Phosphorylation phospho.ELM 17081983
S53 Phosphorylation phospho.ELM 17081983
S168 Phosphorylation PhosphoSitePlus
K175 Acetylation PhosphoSitePlus
K189 Acetylation PhosphoSitePlus
Y345 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
Y414 Phosphorylation PhosphoSitePlus
Y422 Phosphorylation PhosphoSitePlus
K474 Ubiquitination PhosphoSitePlus
K667 Ubiquitination PhosphoSitePlus
K783 Acetylation PhosphoSitePlus
K794 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y414 Phosphorylation HPRD 16497976
Y422 Phosphorylation HPRD 16497976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S168 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K189 Q189 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y345 * Biomuta DOID:1612 / breast cancer [ cosmic ]
Y345 H345 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S349 I349 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K794 M794 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K794 N794 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]