iPTMnet Report for Q59H18 (TNNI3K)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q59H18 / TNI3K_HUMAN
Protein Name Serine/threonine-protein kinase TNNI3K
Gene Name Name: TNNI3K
Synonyms:CARK;
Organism Homo sapiens (Human)

PRO ID PR:Q59H18
DAG View
PRO Name serine/threonine-protein kinase TNNI3K (human)
Definition A serine/threonine-protein kinase TNNI3K that is encoded in the genome of human.
Short Label hTNNI3K
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q59H18 (TNNI3K) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K40 Ubiquitination PhosphoSitePlus
Y62 Phosphorylation PhosphoSitePlus
Y416 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
Y425 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
T581 Phosphorylation PhosphoSitePlus
Y771 Phosphorylation PhosphoSitePlus
Y788 Phosphorylation PhosphoSitePlus
Y804 Phosphorylation PhosphoSitePlus
T805 Phosphorylation PhosphoSitePlus
Y810 Phosphorylation PhosphoSitePlus
Y812 Phosphorylation PhosphoSitePlus
S814 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S424 F424 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S427 F427 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y788 C788 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y804 C804 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y812 H812 Biomuta DOID:1324 / lung cancer [ cosmic ]
S814 Y814 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]