iPTMnet Report for Q58EX2 (SDK2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q58EX2 / SDK2_HUMAN
Protein Name Protein sidekick-2 precursor
Gene Name Name: SDK2
Synonyms:KIAA1514;
Organism Homo sapiens (Human)

PRO ID PR:Q58EX2
DAG View
PRO Name protein sidekick-2 (human)
Definition A protein sidekick-2 that is encoded in the genome of human.
Short Label hSDK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q58EX2 (SDK2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation PhosphoSitePlus
T319 Phosphorylation PhosphoSitePlus
S557 Phosphorylation PhosphoSitePlus
S1024 Phosphorylation PhosphoSitePlus
T1107 Phosphorylation PhosphoSitePlus
S1221 Phosphorylation PhosphoSitePlus
Y1235 Phosphorylation PhosphoSitePlus
K1240 Acetylation PhosphoSitePlus
S1244 Phosphorylation PhosphoSitePlus
T1246 Phosphorylation PhosphoSitePlus
Y1269 Phosphorylation PhosphoSitePlus
Y1272 Phosphorylation PhosphoSitePlus
T1314 Phosphorylation PhosphoSitePlus
T1337 Phosphorylation PhosphoSitePlus
S1417 Phosphorylation PhosphoSitePlus
K1676 Ubiquitination PhosphoSitePlus
S1845 Phosphorylation PhosphoSitePlus
S1999 Phosphorylation PhosphoSitePlus
S2003 Phosphorylation PhosphoSitePlus
K2007 Acetylation PhosphoSitePlus
Y2011 Phosphorylation PhosphoSitePlus
S2014 Phosphorylation PhosphoSitePlus
S2026 Phosphorylation PhosphoSitePlus
Y2033 Phosphorylation PhosphoSitePlus
S2043 Phosphorylation PhosphoSitePlus
T2045 Phosphorylation PhosphoSitePlus
Y2083 Phosphorylation PhosphoSitePlus
S2101 Phosphorylation PhosphoSitePlus
S2105 Phosphorylation PhosphoSitePlus
S2155 Phosphorylation PhosphoSitePlus
S2156 Phosphorylation PhosphoSitePlus
S2170 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K1240 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S1221 R1221 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
Y1235 F1235 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1244 L1244 Biomuta DOID:363 / uterine cancer [ icgc ]
Y1269 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S1417 N1417 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1845 P1845 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S2026 W2026 Biomuta DOID:3565 / meningioma [ cosmic ]
T2045 M2045 Biomuta DOID:5158 / pleural cancer [ cosmic ]
S2101 G2101 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S2170 L2170 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]