iPTMnet Report for Q58A45 (PAN3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q58A45 / PAN3_HUMAN
Protein Name PAN2-PAN3 deadenylation complex subunit PAN3
Gene Name Name: PAN3
Organism Homo sapiens (Human)

PRO ID PR:Q58A45
DAG View
PRO Name PAN2-PAN3 deadenylation complex subunit PAN3 (human)
Definition A PAN2-PAN3 deadenylation complex subunit PAN3 that is encoded in the genome of human.
Short Label hPAN3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q58A45 (PAN3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C58 Methylation IEDB 31844290
K116 Ubiquitination PhosphoSitePlus
T164 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
S192 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
K252 Methylation PhosphoSitePlus
T289 O-Glycosylation GlyGen 35132862, 34105348, 35254053
K296 Ubiquitination PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
T350 Phosphorylation PhosphoSitePlus
T353 Phosphorylation PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus   UniProt 23186163
K496 Methylation PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
K558 Ubiquitination PhosphoSitePlus
K594 Ubiquitination PhosphoSitePlus
K645 Ubiquitination PhosphoSitePlus
T649 O-Glycosylation GlyGen 34105348
K773 Ubiquitination PhosphoSitePlus
K786 Ubiquitination PhosphoSitePlus
K798 Ubiquitination PhosphoSitePlus
K849 Ubiquitination PhosphoSitePlus
S859 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T231 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S192 F192 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S346 F346 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K513 N513 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K645 E645 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]