iPTMnet Report for Q562R1 (ACTBL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q562R1 / ACTBL_HUMAN
Protein Name Beta-actin-like protein 2
Gene Name Name: ACTBL2
Organism Homo sapiens (Human)

PRO ID PR:Q562R1
DAG View
PRO Name beta-actin-like protein 2 (human)
Definition A beta-actin-like protein 2 that is encoded in the genome of human.
Short Label hACTBL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q562R1 (ACTBL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
K51 Acetylation PhosphoSitePlus
K51 Methylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
Y54 Phosphorylation PhosphoSitePlus
K62 Acetylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
R63 Methylation PhosphoSitePlus
K69 Methylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
T107 Phosphorylation PhosphoSitePlus
T121 Phosphorylation HPRD 18452278
Y144 Phosphorylation PhosphoSitePlus
T161 Phosphorylation HPRD   PhosphoSitePlus 20058876
Y170 Phosphorylation HPRD   PhosphoSitePlus 20058876
T187 Phosphorylation PhosphoSitePlus
Y189 Phosphorylation PhosphoSitePlus
K192 Acetylation PhosphoSitePlus
K192 Methylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
Y219 Phosphorylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
T250 Phosphorylation PhosphoSitePlus
C258 Methylation IEDB 31844290
S266 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
C286 S-Nitrosylation dbSNO 2212679, 22126794
K292 Sumoylation PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
Y295 Phosphorylation PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
T305 Phosphorylation PhosphoSitePlus
Y307 Phosphorylation PhosphoSitePlus
R313 Methylation PhosphoSitePlus
T320 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
K329 Acetylation PhosphoSitePlus
K329 Sumoylation PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
K337 Sumoylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S7 Y7 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K69 N69 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T107 I107 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y170 H170 Biomuta DOID:4159 / skin cancer [ cosmic ]
T250 I250 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T250 A250 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
C258 F258 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S266 F266 Biomuta DOID:4159 / skin cancer [ cosmic ]
S266 P266 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y295 F295 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, icgc ]
Y295 S295 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
T298 A298 Biomuta DOID:10534 / stomach cancer [ cosmic ]