iPTMnet Report for Q562F6 (SGO2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q562F6 / SGO2_HUMAN
Protein Name Shugoshin 2
Gene Name Name: SGO2
Synonyms:SGOL2;
Organism Homo sapiens (Human)

PRO ID PR:Q562F6
DAG View
PRO Name shugoshin 2 (human)
Definition A shugoshin 2 that is encoded in the genome of human.
Short Label hSGO2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q562F6 (SGO2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation IEDB 29493099
S34 Phosphorylation PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
S266 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
S268 Phosphorylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus
C291 Methylation IEDB 31844290
S373 Phosphorylation IEDB   PhosphoSitePlus 27920218
K385 Acetylation PhosphoSitePlus
T390 Phosphorylation PhosphoSitePlus
T433 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus
K442 Acetylation PhosphoSitePlus
K471 Acetylation PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
T497 Phosphorylation PhosphoSitePlus
T503 Phosphorylation PhosphoSitePlus
S507 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
K518 Ubiquitination PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
T537 Phosphorylation PhosphoSitePlus
K593 Ubiquitination PhosphoSitePlus
K594 Ubiquitination PhosphoSitePlus
K611 Ubiquitination PhosphoSitePlus
K693 Ubiquitination PhosphoSitePlus
T720 Phosphorylation PhosphoSitePlus
S743 Phosphorylation PhosphoSitePlus
K751 Ubiquitination PhosphoSitePlus
S774 Phosphorylation PhosphoSitePlus
Y778 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S780 Phosphorylation PhosphoSitePlus
K831 Ubiquitination PhosphoSitePlus
K838 Ubiquitination PhosphoSitePlus
S843 Phosphorylation PhosphoSitePlus
T845 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 16565220
K887 Ubiquitination PhosphoSitePlus
Y924 Phosphorylation PhosphoSitePlus
K939 Ubiquitination PhosphoSitePlus
K960 Ubiquitination PhosphoSitePlus
S1028 Phosphorylation PhosphoSitePlus
S1032 Phosphorylation PhosphoSitePlus
K1070 Methylation PhosphoSitePlus
K1074 Acetylation PhosphoSitePlus
T1084 Phosphorylation PhosphoSitePlus
S1085 Phosphorylation PhosphoSitePlus
S1089 Phosphorylation PhosphoSitePlus
S1102 Phosphorylation PhosphoSitePlus
K1106 Ubiquitination PhosphoSitePlus
S1138 Phosphorylation PhosphoSitePlus
S1140 Phosphorylation PhosphoSitePlus
S1144 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1150 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1151 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1154 Phosphorylation PhosphoSitePlus
S1163 Phosphorylation PhosphoSitePlus
S1165 Phosphorylation PhosphoSitePlus
S1166 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1181 Phosphorylation PhosphoSitePlus
S1187 Phosphorylation PhosphoSitePlus
S1208 Phosphorylation PhosphoSitePlus
S1222 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S266 Phosphorylation HPRD 19691289, 16565220
S373 Phosphorylation HPRD 19664995
S421 Phosphorylation HPRD 19007248
S436 Phosphorylation HPRD 19691289
T497 Phosphorylation HPRD 19007248, 19691289
S507 Phosphorylation HPRD 17525332, 18077418
Y778 Phosphorylation HPRD 18669648
T845 Phosphorylation HPRD 18669648, 20058876, 20068231, ...16565220
T1084 Phosphorylation HPRD 19691289
S1085 Phosphorylation HPRD 19691289
S1140 Phosphorylation HPRD 20068231
S1144 Phosphorylation HPRD 18669648, 19691289, 20068231
S1150 Phosphorylation HPRD 18669648, 20068231
S1151 Phosphorylation HPRD 18669648, 20068231
S1166 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S34 F34 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S34 Y34 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K385 I385 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T433 A433 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T497 A497 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S507 F507 Biomuta DOID:4159 / skin cancer [ cosmic ]
T537 I537 Biomuta DOID:1319 / brain cancer [ cosmic ]
K594 R594 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S743 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S780 F780 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K838 N838 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1085 F1085 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1102 N1102 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K1106 N1106 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S1138 Y1138 Biomuta DOID:363 / uterine cancer [ icgc ]
S1144 L1144 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S1150 F1150 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1187 I1187 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1208 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]