iPTMnet Report for Q53RE8 (ANKRD39)
Protein Information
UniProt AC / UniProt ID | Q53RE8 / ANR39_HUMAN |
Protein Name | Ankyrin repeat domain-containing protein 39 |
Gene Name | Name: ANKRD39 ORFNames:HSPC200; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q53RE8 |
PRO Name | ankyrin repeat domain-containing protein 39 (human) |
Definition | An ankyrin repeat domain-containing protein 39 that is encoded in the genome of human. |
Short Label | hANKRD39 |
Category | organism-gene |
Q53RE8 (ANKRD39) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K48 | Ubiquitination | score1 | PhosphoSitePlus | |||
K53 | Ubiquitination | score1 | PhosphoSitePlus | |||
S62 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y65 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 15592455 | ||
T66 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y70 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y106 | Phosphorylation | score1 | PhosphoSitePlus | |||
S121 | Phosphorylation | score1 | PhosphoSitePlus | |||
K136 | Ubiquitination | score1 | PhosphoSitePlus | |||
C146 | Methylation | score1 | IEDB | 31844290 | ||
S153 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
K157 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K53 | E53 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S62 | L62 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:5158 / pleural cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
T66 | I66 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S121 | P121 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
C146 | Y146 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S153 | N153 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |