iPTMnet Report for Q53R41 (FASTKD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q53R41 / FAKD1_HUMAN
Protein Name FAST kinase domain-containing protein 1, mitochondrial precursor
Gene Name Name: FASTKD1
Synonyms:KIAA1800;
Organism Homo sapiens (Human)

PRO ID PR:Q53R41
DAG View
PRO Name FAST kinase domain-containing protein 1, mitochondrial (human)
Definition A FAST kinase domain-containing protein 1, mitochondrial that is encoded in the genome of human.
Short Label hFASTKD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q53R41 (FASTKD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K60 Ubiquitination PhosphoSitePlus
T83 Phosphorylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
Y122 Phosphorylation PhosphoSitePlus
T124 Phosphorylation PhosphoSitePlus
Y168 Phosphorylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
K360 Acetylation PhosphoSitePlus   UniProt 19608861
K374 Ubiquitination PhosphoSitePlus
S405 Phosphorylation PhosphoSitePlus
Y406 Phosphorylation PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
K482 Ubiquitination PhosphoSitePlus
Y486 Phosphorylation PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus
T546 Phosphorylation PhosphoSitePlus
T551 Phosphorylation PhosphoSitePlus
S619 Phosphorylation IEDB 32387766
K691 Ubiquitination PhosphoSitePlus
C716 Methylation IEDB 31844290
Y726 Phosphorylation PhosphoSitePlus
K728 Ubiquitination PhosphoSitePlus
K737 Ubiquitination PhosphoSitePlus
K785 Ubiquitination PhosphoSitePlus
Y810 Phosphorylation PhosphoSitePlus
K844 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K374 T374 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y486 C486 Biomuta DOID:3571 / liver cancer [ cosmic ]
S619 F619 Biomuta DOID:4159 / skin cancer [ cosmic ]
S619 C619 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K728 I728 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K728 N728 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]