iPTMnet Report for Q53HL2 (CDCA8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q53HL2 / BOREA_HUMAN
Protein Name Borealin
Gene Name Name: CDCA8
Synonyms:PESCRG3;
Organism Homo sapiens (Human)

PRO ID PR:Q53HL2
DAG View
PRO Name borealin (human)
Definition A borealin that is encoded in the genome of human.
Short Label hCDCA8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q53HL2 (CDCA8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Sumoylation PRO
K5 Acetylation PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
T13 Phosphorylation HPRD 20068231
S15 Phosphorylation HPRD   PhosphoSitePlus 18691976, 20068231, 20068230
K20 Ubiquitination PhosphoSitePlus
S23 Phosphorylation HPRD   PhosphoSitePlus 18691976
K37 Ubiquitination PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
T88 Phosphorylation P33981 (TTK) phospho.ELM   PhosphoSitePlus   Signor   UniProt 19530738, 18243099
T94 Phosphorylation P33981 (TTK) phospho.ELM   PhosphoSitePlus   Signor   UniProt 19530738, 18243099
K98 Ubiquitination PhosphoSitePlus
T100 Phosphorylation PhosphoSitePlus
T106 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18691976, 17287340, 17241471, ...19007248, 19664995, 22067460, 18669648, 23186163, 19690332
K109 Ubiquitination PhosphoSitePlus
S110 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976
K112 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
T152 Phosphorylation PhosphoSitePlus
S154 Phosphorylation Q96GD4 (AURKB) HPRD   neXtProt   PhosphoSitePlus   RLIMS-P 18691976, 19007248, 17483322
S164 Phosphorylation HPRD   PhosphoSitePlus 18691976, 19691289
S165 Phosphorylation Q96GD4 (AURKB) HPRD   PhosphoSitePlus   RLIMS-P   UniProt 17241471, 15249581, 28004745, ...18691976
T169 Phosphorylation P33981 (TTK) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 19530738, 19007248, 18243099
T171 Phosphorylation HPRD   PhosphoSitePlus 19007248
S180 Phosphorylation HPRD   PhosphoSitePlus 19007248, 20068231
K183 Ubiquitination PhosphoSitePlus
T185 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
T189 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 19691289, ...18669648, 20068231
S194 Phosphorylation HPRD   PhosphoSitePlus 18691976
K198 Ubiquitination PhosphoSitePlus
T199 Phosphorylation HPRD   PhosphoSitePlus 19007248, 19691289
T204 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 19007248, ...19691289, 18669648
S215 Phosphorylation HPRD   PhosphoSitePlus 19007248, 19691289
S219 Phosphorylation Q96GD4 (AURKB) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 19413330, 21406692, 17287340, ...18212344, 18691976, 22067460, 20058876, 19007248, 17483322, 16565220, 19651622, 20803554, 18669648, 19664995, 19369195, 23186163, 19690332, 20068231, 19691289
S224 Phosphorylation PhosphoSitePlus   UniProt 19369195
K225 Ubiquitination PhosphoSitePlus
T230 Phosphorylation P33981 (TTK) phospho.ELM   PhosphoSitePlus   Signor   UniProt 19530738, 18243099
S238 Phosphorylation P33981 (TTK) PhosphoSitePlus   UniProt 19530738
S244 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 19691289
S250 Phosphorylation HPRD   PhosphoSitePlus 20068231
K263 Ubiquitination PhosphoSitePlus
C273 Methylation IEDB 31844290
S274 Phosphorylation HPRD   PhosphoSitePlus 18691976
S275 Phosphorylation Q96GD4 (AURKB) HPRD   neXtProt   PhosphoSitePlus   RLIMS-P 19691289, 17483322
T278 Phosphorylation Q96GD4 (AURKB) neXtProt   PhosphoSitePlus   RLIMS-P 17483322


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046668 (hCDCA8/SumoLys+) su PRO


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:Q53HL2 (hCDCA8) Interaction PR:O15392 (hBIRC5) PRO
PR:Q53HL2 (hCDCA8) Interaction PR:Q9NQS7 (hINCENP) PRO
PR:Q53HL2 (hCDCA8) Interaction PR:Q71DI3 (hH3.2) PRO
PR:Q53HL2 (hCDCA8) Interaction PR:Q96GD4 (hAURKB) PRO
PR:Q53HL2 (hCDCA8) Interaction PR:Q5FBB7 (hSGO1) PRO
PR:Q5FBB7 (hSGO1) Interaction PR:Q53HL2 (hCDCA8) PRO
PR:Q96GD4 (hAURKB) Interaction PR:Q53HL2 (hCDCA8) PRO
PR:Q9NQS7 (hINCENP) Interaction PR:Q53HL2 (hCDCA8) PRO