iPTMnet Report for Q53HC5 (KLHL26)
Protein Information
| UniProt AC / UniProt ID | Q53HC5 / KLH26_HUMAN |
| Protein Name | Kelch-like protein 26 |
| Gene Name | Name: KLHL26 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q53HC5 |
| PRO Name | kelch-like protein 26 (human) |
| Definition | A kelch-like protein 26 that is encoded in the genome of human. |
| Short Label | hKLHL26 |
| Category | organism-gene |
Q53HC5 (KLHL26) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330 | ||
| S44 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S48 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T68 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y331 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S426 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K447 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K476 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K491 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K560 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| A2 | E2 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S44 | T44 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| S48 | N48 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| K447 | Q447 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K491 | Q491 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K560 | R560 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] |
DAG View