Protein Information

Cytoscape View


UniProt AC / UniProt ID Q53H54 / TYW2_HUMAN
Protein Name tRNA wybutosine-synthesizing protein 2 homolog
Gene Name Name: TRMT12
Synonyms:TRM12,TYW2;
Organism Homo sapiens (Human)

PRO ID PR:Q53H54
DAG View
PRO Name tRNA wybutosine-synthesizing protein 2 homolog (human)
Definition A tRNA wybutosine-synthesizing protein 2 that is encoded in the genome of human.
Short Label hTRMT12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q53H54 (TRMT12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K51 Ubiquitination PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
S180 O-Glycosylation GlyGen 30379171, 29351928
C215 Methylation IEDB 31844290
K298 Ubiquitination PhosphoSitePlus
K354 Ubiquitination PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
T367 O-Glycosylation GlyGen 30379171, 29351928
T368 O-Glycosylation GlyGen 30379171, 29351928


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K357 N357 Biomuta DOID:9256 / colorectal cancer [ cosmic ]