Protein Information

Cytoscape View

UniProt AC / UniProt ID Q53H47 / SETMR_HUMAN
Protein Name Histone-lysine N-methyltransferase SETMAR
Gene Name Name: SETMAR
Organism Homo sapiens (Human)

DAG View
PRO Name histone-lysine N-methyltransferase SETMAR (human)
Definition A histone-lysine N-methyltransferase SETMAR that is encoded in the genome of human.
Short Label hSETMAR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q53H47 (SETMAR) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K275 Ubiquitination PhosphoSitePlus
K335 Methylation PhosphoSitePlus
T338 Phosphorylation PhosphoSitePlus
T341 Phosphorylation PhosphoSitePlus
K343 Acetylation PhosphoSitePlus
K348 Acetylation PhosphoSitePlus
K391 Acetylation PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
S410 Phosphorylation PhosphoSitePlus
K448 Acetylation PhosphoSitePlus
K498 Methylation PhosphoSitePlus   UniProt 18790802
S508 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 22231448, ...19690332, 20068231
S508 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 22231448
K523 Ubiquitination PhosphoSitePlus
K569 Ubiquitination PhosphoSitePlus
K637 Ubiquitination PhosphoSitePlus
K674 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S508 Phosphorylation HPRD 19664994, 20068231

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K348 R348 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S410 T410 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]