iPTMnet Report for Q53GT1 (KLHL22)
Protein Information
| UniProt AC / UniProt ID | Q53GT1 / KLH22_HUMAN |
| Protein Name | Kelch-like protein 22 |
| Gene Name | Name: KLHL22 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q53GT1 |
| PRO Name | kelch-like protein 22 (human) |
| Definition | A kelch-like protein 22 that is encoded in the genome of human. |
| Short Label | hKLHL22 |
| Category | organism-gene |
DAG ViewQ53GT1 (KLHL22) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22223895 | ||
| K12 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K260 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S281 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K319 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K433 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C465 | Methylation | score1 | IEDB | 31844290 | ||
| K494 | Acetylation | score1 | PhosphoSitePlus | |||
| C516 | Methylation | score1 | IEDB | 31844290 | ||
| Y517 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T605 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S18 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S18 | L18 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
