iPTMnet Report for Q53GS7 (GLE1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q53GS7 / GLE1_HUMAN
Protein Name mRNA export factor GLE1
Gene Name Name: GLE1
Synonyms:GLE1L;
Organism Homo sapiens (Human)

PRO ID PR:Q53GS7
DAG View
PRO Name mRNA export factor GLE1 (human)
Definition An mRNA export factor GLE1 that is encoded in the genome of human.
Short Label hGLE1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q53GS7 (GLE1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K12 Methylation PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
C23 Methylation IEDB 31844290
S41 Phosphorylation PhosphoSitePlus   UniProt 23186163
S88 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332, 20068231
S92 Phosphorylation PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus   UniProt 20068231
T102 Phosphorylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
Y135 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K157 Acetylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
K176 Acetylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
C400 Methylation IEDB 31844290
K419 Ubiquitination PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
K440 Ubiquitination PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
K447 Ubiquitination PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
K455 Ubiquitination PhosphoSitePlus
Y478 Phosphorylation PhosphoSitePlus
K479 Ubiquitination PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
K486 Ubiquitination PhosphoSitePlus
K526 Ubiquitination PhosphoSitePlus
K527 Ubiquitination PhosphoSitePlus
K539 Ubiquitination PhosphoSitePlus
K556 Ubiquitination PhosphoSitePlus
K559 Ubiquitination PhosphoSitePlus
K568 Ubiquitination PhosphoSitePlus
C629 Methylation IEDB 31844290
Y652 Phosphorylation PhosphoSitePlus
K672 Ubiquitination PhosphoSitePlus
K677 Ubiquitination PhosphoSitePlus
K682 Ubiquitination PhosphoSitePlus
K688 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation HPRD 20068231
S88 Phosphorylation HPRD 19691289, 20068231
S92 Phosphorylation HPRD 20068231
S99 Phosphorylation HPRD 20068231
T102 Phosphorylation HPRD 20068231
S300 Phosphorylation HPRD 20068231
S301 Phosphorylation HPRD 20068231
S463 Phosphorylation HPRD 20068231
T467 Phosphorylation HPRD 20068231
Y478 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation HPRD 20068231
S88 Phosphorylation HPRD 19691289, 20068231
S92 Phosphorylation HPRD 20068231
S99 Phosphorylation HPRD 20068231
T102 Phosphorylation HPRD   PhosphoSitePlus 20068231
S300 Phosphorylation HPRD 20068231
S301 Phosphorylation HPRD 20068231
S463 Phosphorylation HPRD 20068231
T467 Phosphorylation HPRD 20068231
Y478 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S16 I16 Biomuta DOID:3571 / liver cancer [ cosmic ]
S41 P41 Biomuta DOID:363 / uterine cancer [ icgc ]
S88 F88 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S96 F96 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
K157 R157 Biomuta DOID:1612 / breast cancer [ cosmic ]
K179 N179 Biomuta DOID:3571 / liver cancer [ cosmic ]
K238 N238 Biomuta DOID:363 / uterine cancer [ icgc ]
S450 N450 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y652 C652 Biomuta DOID:1324 / lung cancer [ cosmic ]