iPTMnet Report for Q53GL0 (PLEKHO1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q53GL0 / PKHO1_HUMAN
Protein Name Pleckstrin homology domain-containing family O member 1
Gene Name Name: PLEKHO1
Synonyms:CKIP1,OC120;ORFNames:HQ0024c;
Organism Homo sapiens (Human)

PRO ID PR:Q53GL0
DAG View
PRO Name pleckstrin homology domain-containing family O member 1 (human)
Definition A pleckstrin homology domain-containing family O member 1 that is encoded in the genome of human.
Short Label hPLEKHO1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q53GL0 (PLEKHO1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
T247 Phosphorylation PhosphoSitePlus
Y253 Phosphorylation PhosphoSitePlus
T254 Phosphorylation PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
T264 Phosphorylation PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S271 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S238 G238 Biomuta DOID:4159 / skin cancer [ cosmic ]
T247 P247 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S271 F271 Biomuta DOID:4159 / skin cancer [ cosmic ]
S363 P363 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S364 L364 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ]