iPTMnet Report for Q53G59 (KLHL12)
Protein Information
| UniProt AC / UniProt ID | Q53G59 / KLH12_HUMAN |
| Protein Name | Kelch-like protein 12 |
| Gene Name | Name: KLHL12 Synonyms:C3IP1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q53G59 |
| PRO Name | kelch-like protein 12 (human) |
| Definition | A kelch-like protein 12 that is encoded in the genome of human. |
| Short Label | hKLHL12 |
| Category | organism-gene |
DAG ViewQ53G59 (KLHL12) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T31 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C33 | Methylation | score1 | IEDB | 31844290 | ||
| T36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C111 | Methylation | score1 | IEDB | 31844290 | ||
| K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S175 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y231 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K305 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K462 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C511 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C111 | Y111 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| C111 | S111 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K181 | T181 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K301 | N301 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| C511 | W511 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
