iPTMnet Report for Q53EP0 (FNDC3B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q53EP0 / FND3B_HUMAN
Protein Name Fibronectin type III domain-containing protein 3B
Gene Name Name: FNDC3B
Synonyms:FAD104,NS5ABP37;ORFNames:UNQ2421/PRO4979/PRO34274;
Organism Homo sapiens (Human)

PRO ID PR:Q53EP0
DAG View
PRO Name fibronectin type III domain-containing protein 3B (human)
Definition A fibronectin type III domain-containing protein 3B that is encoded in the genome of human.
Short Label hFNDC3B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q53EP0 (FNDC3B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y175 Phosphorylation PhosphoSitePlus
Y180 Phosphorylation PhosphoSitePlus
S208 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S211 Phosphorylation PhosphoSitePlus
Y214 Phosphorylation PhosphoSitePlus
K215 Methylation PhosphoSitePlus
Y222 Phosphorylation PhosphoSitePlus
K227 Methylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
Y265 Phosphorylation PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
Y351 Phosphorylation PhosphoSitePlus
Y359 Phosphorylation PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
K408 Ubiquitination PhosphoSitePlus
K420 Ubiquitination PhosphoSitePlus
C442 Methylation IEDB 31844290
Y469 Phosphorylation PhosphoSitePlus
T492 Phosphorylation PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus
T532 Phosphorylation PhosphoSitePlus
K536 Ubiquitination PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
K581 Ubiquitination PhosphoSitePlus
C674 Methylation IEDB 31844290
C885 Methylation IEDB 31844290
K951 Ubiquitination PhosphoSitePlus
K953 Ubiquitination PhosphoSitePlus
K977 Ubiquitination PhosphoSitePlus
T1014 Phosphorylation PhosphoSitePlus
K1051 Ubiquitination PhosphoSitePlus
T1056 Phosphorylation PhosphoSitePlus
Y1103 Phosphorylation PhosphoSitePlus
K1104 Ubiquitination PhosphoSitePlus
Y1121 Phosphorylation PhosphoSitePlus
S1153 Phosphorylation PhosphoSitePlus
T1158 Phosphorylation PhosphoSitePlus
S1163 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Site PTM Type PTM Enzyme Score Source PMID
S208 Phosphorylation HPRD 18669648, 19664994, 20068231, ...17924679
S211 Phosphorylation HPRD 17924679
S1163 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S211 F211 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y359 H359 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C442 Y442 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T532 S532 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K953 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]