iPTMnet Report for Q4V328 (GRIPAP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q4V328 / GRAP1_HUMAN
Protein Name GRIP1-associated protein 1
Gene Name Name: GRIPAP1
Synonyms:KIAA1167;
Organism Homo sapiens (Human)

PRO ID PR:Q4V328
DAG View
PRO Name GRIP1-associated protein 1 (human)
Definition A GRIP1-associated protein 1 that is encoded in the genome of human.
Short Label hGRIPAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q4V328 (GRIPAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 22223895
K33 Ubiquitination PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
R296 Methylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
T440 Phosphorylation PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
C581 Methylation IEDB 31844290
K584 Ubiquitination PhosphoSitePlus
T596 Phosphorylation PhosphoSitePlus
T637 Phosphorylation PhosphoSitePlus
K640 Ubiquitination PhosphoSitePlus
S641 Phosphorylation PhosphoSitePlus
S655 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 18220336
T659 O-Glycosylation GlyGen 30379171, 28657654
S665 Phosphorylation PhosphoSitePlus
S666 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S668 Phosphorylation PhosphoSitePlus
S669 Phosphorylation PhosphoSitePlus
S671 Phosphorylation PhosphoSitePlus
Y672 Phosphorylation PhosphoSitePlus
K679 Ubiquitination PhosphoSitePlus
S688 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
S690 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 19690332
S691 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
S692 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 19690332
S704 Phosphorylation PhosphoSitePlus
K722 Ubiquitination PhosphoSitePlus
K728 Ubiquitination PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
K746 Ubiquitination PhosphoSitePlus
S775 Phosphorylation PhosphoSitePlus
K782 Ubiquitination PhosphoSitePlus
K794 Ubiquitination PhosphoSitePlus
K805 Ubiquitination PhosphoSitePlus
K811 Acetylation PhosphoSitePlus
K825 Ubiquitination PhosphoSitePlus
S841 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T247 Phosphorylation HPRD 20068231
T251 Phosphorylation HPRD 20068231
T637 Phosphorylation HPRD 20068231
S655 Phosphorylation HPRD 17322306, 18669648, 19415658, ...20068231
S664 Phosphorylation HPRD 20068231
S665 Phosphorylation HPRD 19651622
S666 Phosphorylation HPRD 19651622, 20068231
S668 Phosphorylation HPRD 19651622, 20068231
S669 Phosphorylation HPRD 19651622
Y672 Phosphorylation HPRD 20068231
S688 Phosphorylation HPRD 19651622, 18669648, 20068231
S690 Phosphorylation HPRD 18669648, 17081983, 20068231
S691 Phosphorylation HPRD 18669648, 17081983, 20068231
S692 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K33 N33 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S73 N73 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S222 F222 Biomuta DOID:4159 / skin cancer [ cosmic ]
T247 R247 Biomuta [ cosmic ]
S318 F318 Biomuta [ cosmic ]
S655 L655 Biomuta DOID:3571 / liver cancer [ cosmic, tcga ]
S665 G665 Biomuta DOID:363 / uterine cancer [ cosmic ]
S688 F688 Biomuta DOID:4159 / skin cancer [ cosmic ]