iPTMnet Report for Q4U2R8 (SLC22A6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q4U2R8 / S22A6_HUMAN
Protein Name Solute carrier family 22 member 6
Gene Name Name: SLC22A6
Synonyms:OAT1,PAHT;
Organism Homo sapiens (Human)

PRO ID PR:Q4U2R8
DAG View
PRO Name solute carrier family 22 member 6 (human)
Definition A solute carrier family 22 member 6 that is encoded in the genome of human.
Short Label hSLC22A6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q4U2R8 (SLC22A6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N39 N-Glycosylation GlyGen   UniProt 14749323
N56 N-Glycosylation GlyGen   UniProt 14749323
N92 N-Glycosylation GlyGen   UniProt 14749323
N97 N-Glycosylation GlyGen   UniProt 14749323
N113 N-Glycosylation GlyGen   UniProt 10462545
K297 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
T318 Phosphorylation PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N113 T113 Biomuta DOID:4159 / skin cancer [ cosmic ]
K315 N315 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S325 L325 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]