iPTMnet Report for Q4LE39 (ARID4B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q4LE39 / ARI4B_HUMAN
Protein Name AT-rich interactive domain-containing protein 4B
Gene Name Name: ARID4B
Synonyms:BRCAA1,RBBP1L1,RBP1L1,SAP180;
Organism Homo sapiens (Human)

PRO ID PR:Q4LE39
DAG View
PRO Name AT-rich interactive domain-containing protein 4B (human)
Definition An AT-rich interactive domain-containing protein 4B that is encoded in the genome of human.
Short Label hARID4B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q4LE39 (ARID4B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K28 Ubiquitination PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
Y89 Phosphorylation PhosphoSitePlus
T90 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
T126 Phosphorylation PhosphoSitePlus
T133 Phosphorylation PhosphoSitePlus
T140 Phosphorylation IEDB 32387766
K257 Ubiquitination PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus   UniProt 21406692
S295 Phosphorylation PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
Y335 Phosphorylation PhosphoSitePlus
C420 Methylation IEDB 31844290
K429 Sumoylation PhosphoSitePlus
K440 Sumoylation PhosphoSitePlus
K466 Ubiquitination PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
S483 Phosphorylation PhosphoSitePlus   UniProt 23186163
T507 Phosphorylation PhosphoSitePlus
T508 Phosphorylation PhosphoSitePlus
K647 Acetylation PhosphoSitePlus
K649 Acetylation PhosphoSitePlus
K654 Acetylation PhosphoSitePlus
Y655 Phosphorylation PhosphoSitePlus
S656 Phosphorylation PhosphoSitePlus
S666 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T672 Phosphorylation PhosphoSitePlus
S675 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K688 Ubiquitination PhosphoSitePlus
S717 Phosphorylation PhosphoSitePlus   UniProt 17081983
K751 Ubiquitination PhosphoSitePlus
S758 Phosphorylation PhosphoSitePlus
S776 Phosphorylation PhosphoSitePlus
S778 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...20068231
S790 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18669648, ...19690332, 20068231
T793 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18669648, ...19690332, 20068231
Y795 Phosphorylation PhosphoSitePlus
Y827 Phosphorylation PhosphoSitePlus
T830 Phosphorylation PhosphoSitePlus
T836 Phosphorylation PhosphoSitePlus
S838 Phosphorylation PhosphoSitePlus
T874 Phosphorylation PhosphoSitePlus
K878 Acetylation PhosphoSitePlus
S888 Phosphorylation PhosphoSitePlus
Y895 Phosphorylation PhosphoSitePlus
S896 Phosphorylation PhosphoSitePlus
S899 Phosphorylation PhosphoSitePlus
K904 Acetylation PhosphoSitePlus
K904 Ubiquitination PhosphoSitePlus
S912 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S919 Phosphorylation PhosphoSitePlus
S930 Phosphorylation PhosphoSitePlus
S1014 Phosphorylation PhosphoSitePlus   UniProt 19690332
T1022 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
T1025 Phosphorylation PhosphoSitePlus
T1026 Phosphorylation PhosphoSitePlus   UniProt 19690332
S1029 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 23186163
S1031 Phosphorylation PhosphoSitePlus
S1032 Phosphorylation PhosphoSitePlus
T1036 Phosphorylation PhosphoSitePlus
S1060 Phosphorylation PhosphoSitePlus
K1131 Acetylation PhosphoSitePlus
T1150 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1152 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1153 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1155 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1159 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1174 Phosphorylation PhosphoSitePlus
K1178 Acetylation PhosphoSitePlus
K1183 Acetylation PhosphoSitePlus
S1184 Phosphorylation PhosphoSitePlus
S1190 Phosphorylation PhosphoSitePlus
K1245 Ubiquitination PhosphoSitePlus
S1256 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T133 Phosphorylation HPRD 20068231
S273 Phosphorylation HPRD 19651622, 18452278
S274 Phosphorylation HPRD 19651622, 18452278
S275 Phosphorylation HPRD 18452278
S276 Phosphorylation HPRD 19651622, 18452278
S295 Phosphorylation HPRD 19651622, 18452278
S296 Phosphorylation HPRD 19651622, 20068231, 18452278
S483 Phosphorylation HPRD 20068231
T507 Phosphorylation HPRD 20068231
T508 Phosphorylation HPRD 20068231
S666 Phosphorylation HPRD 18669648
S675 Phosphorylation HPRD 19413330, 18669648, 20068231
S710 Phosphorylation HPRD 17081983
S712 Phosphorylation HPRD 17081983
S713 Phosphorylation HPRD 17081983
S717 Phosphorylation HPRD 17081983, 18452278
S776 Phosphorylation HPRD 17081983, 20068231
S778 Phosphorylation HPRD 20068231
S790 Phosphorylation HPRD 19413330, 18452278, 19651622, ...18669648, 19415658, 20068231
T793 Phosphorylation HPRD 19413330, 17081983, 18452278, ...19651622, 18669648, 19415658, 20068231
Y795 Phosphorylation HPRD 19413330, 17081983
S912 Phosphorylation HPRD 18669648, 20068231
T1150 Phosphorylation HPRD 18669648, 20068231
S1152 Phosphorylation HPRD 18669648
S1153 Phosphorylation HPRD 19413330, 18669648, 18452278
S1155 Phosphorylation HPRD 19413330, 18669648
S1159 Phosphorylation HPRD 18669648
S1252 Phosphorylation HPRD 18691976
S1256 Phosphorylation HPRD 18691976
Site PTM Type PTM Enzyme Score Source PMID
T133 Phosphorylation HPRD 20068231
S273 Phosphorylation HPRD 19651622, 18452278
S274 Phosphorylation HPRD 19651622, 18452278
S275 Phosphorylation HPRD 18452278
S276 Phosphorylation HPRD 19651622, 18452278
S295 Phosphorylation HPRD 19651622, 18452278
S296 Phosphorylation HPRD 19651622, 20068231, 18452278
S483 Phosphorylation HPRD 20068231
T507 Phosphorylation HPRD 20068231
T508 Phosphorylation HPRD 20068231
S580 Phosphorylation HPRD 18669648
S589 Phosphorylation HPRD 19413330, 18669648, 20068231
S624 Phosphorylation HPRD 17081983
S626 Phosphorylation HPRD 17081983
S627 Phosphorylation HPRD 17081983
S631 Phosphorylation HPRD 17081983, 18452278
S690 Phosphorylation HPRD 17081983, 20068231
S692 Phosphorylation HPRD 20068231
S704 Phosphorylation HPRD 19413330, 18452278, 19651622, ...18669648, 19415658, 20068231
T707 Phosphorylation HPRD   PhosphoSitePlus 19413330, 17081983, 18452278, ...19651622, 18669648, 19415658, 20068231
Y709 Phosphorylation HPRD 19413330, 17081983
S826 Phosphorylation HPRD 18669648, 20068231
T1064 Phosphorylation HPRD 18669648, 20068231
S1066 Phosphorylation HPRD 18669648
S1067 Phosphorylation HPRD 19413330, 18669648, 18452278
S1069 Phosphorylation HPRD 19413330, 18669648
S1073 Phosphorylation HPRD 18669648
S1166 Phosphorylation HPRD 18691976
S1170 Phosphorylation HPRD 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K28 N28 Biomuta DOID:363 / uterine cancer [ icgc ]
T126 I126 Biomuta DOID:4159 / skin cancer [ cosmic ]
K257 R257 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S274 P274 Biomuta DOID:1324 / lung cancer [ cosmic ]
T507 I507 Biomuta DOID:1319 / brain cancer [ cosmic ]
T508 A508 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S624 F624 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S627 Y627 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S656 C656 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K688 R688 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K688 Q688 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S710 F710 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S713 Y713 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K751 E751 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S838 A838 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S888 F888 Biomuta DOID:4159 / skin cancer [ cosmic ]
S899 L899 Biomuta DOID:4159 / skin cancer [ cosmic ]
S930 N930 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S1066 R1066 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1073 T1073 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
K1131 R1131 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1152 R1152 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1159 T1159 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1174 F1174 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1184 Y1184 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]