Protein Information

Cytoscape View

UniProt AC / UniProt ID Q4L235 / ACSF4_HUMAN
Protein Name Beta-alanine-activating enzyme
Gene Name Name: AASDH
Organism Homo sapiens (Human)

DAG View
PRO Name beta-alanine-activating enzyme (human)
Definition A beta-alanine-activating enzyme that is encoded in the genome of human.
Short Label hAASDH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q4L235 (AASDH) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K9 Ubiquitination PhosphoSitePlus
K164 Acetylation PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
T338 Phosphorylation PhosphoSitePlus
K499 Ubiquitination PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
K591 Acetylation PhosphoSitePlus
T644 Phosphorylation PhosphoSitePlus
S649 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
K698 Ubiquitination PhosphoSitePlus
S724 Phosphorylation PhosphoSitePlus   UniProt 23186163
K765 Acetylation PhosphoSitePlus
Y870 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T338 K338 Biomuta DOID:3571 / liver cancer [ icgc ]
K765 N765 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]