iPTMnet Report for Q4L180 (FILIP1L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q4L180 / FIL1L_HUMAN
Protein Name Filamin A-interacting protein 1-like
Gene Name Name: FILIP1L
Synonyms:COL4A3BPIP,DOC1,GIP90;
Organism Homo sapiens (Human)

PRO ID PR:Q4L180
DAG View
PRO Name filamin A-interacting protein 1-like (human)
Definition A filamin A-interacting protein 1-like that is encoded in the genome of human.
Short Label hFILIP1L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q4L180 (FILIP1L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K14 Ubiquitination PhosphoSitePlus
K21 Acetylation PhosphoSitePlus
T340 Phosphorylation PhosphoSitePlus
K385 Acetylation PhosphoSitePlus
S459 Phosphorylation PhosphoSitePlus
T485 Phosphorylation PhosphoSitePlus
T495 Phosphorylation PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus
T768 Phosphorylation PhosphoSitePlus
S778 Phosphorylation PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus
S784 Phosphorylation PhosphoSitePlus
S791 O-Glycosylation GlyGen 30379171, 34019948, 28657654, ...35254053
S791 Phosphorylation IEDB   PhosphoSitePlus   UniProt 24275569, 27869121
S846 Phosphorylation PhosphoSitePlus
S974 Phosphorylation PhosphoSitePlus
T986 Phosphorylation PhosphoSitePlus
S992 Phosphorylation PhosphoSitePlus
T994 Phosphorylation PhosphoSitePlus
S1000 Phosphorylation PhosphoSitePlus
S1013 Phosphorylation PhosphoSitePlus
S1019 Phosphorylation PhosphoSitePlus
S1035 Phosphorylation PhosphoSitePlus
S1041 Phosphorylation PhosphoSitePlus
S1047 Phosphorylation PhosphoSitePlus
S1049 Phosphorylation PhosphoSitePlus
S1051 Phosphorylation PhosphoSitePlus
S1053 Phosphorylation PhosphoSitePlus
S1076 Phosphorylation PhosphoSitePlus
S1082 Phosphorylation PhosphoSitePlus
T1108 O-Glycosylation GlyGen 30379171, 34019948, 28657654, ...35254053
T1114 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T340 Phosphorylation HPRD 19413330
T495 Phosphorylation HPRD 20068231
T693 Phosphorylation HPRD 20068231
S712 Phosphorylation HPRD 20068231
S791 Phosphorylation HPRD 20166139
Site PTM Type PTM Enzyme Score Source PMID
T340 Phosphorylation HPRD 19413330
T495 Phosphorylation HPRD 20068231
T693 Phosphorylation HPRD 20068231
S712 Phosphorylation HPRD 20068231
S791 Phosphorylation HPRD 20166139
Site PTM Type PTM Enzyme Score Source PMID
T100 Phosphorylation HPRD 19413330
T255 Phosphorylation HPRD 20068231
T453 Phosphorylation HPRD 20068231
S472 Phosphorylation HPRD 20068231
S551 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K14 Q14 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K14 N14 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S551 F551 Biomuta DOID:4159 / skin cancer [ cosmic ]
S791 F791 Biomuta DOID:4159 / skin cancer [ cosmic ]
S974 P974 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T994 I994 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
S1019 F1019 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1041 L1041 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]