iPTMnet Report for Q4KMZ1 (IQCC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q4KMZ1 / IQCC_HUMAN
Protein Name IQ domain-containing protein C
Gene Name Name: IQCC
Organism Homo sapiens (Human)

PRO ID PR:Q4KMZ1
DAG View
PRO Name IQ domain-containing protein C (human)
Definition An IQ domain-containing protein C that is encoded in the genome of human.
Short Label hIQCC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q4KMZ1 (IQCC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K63 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
T149 Phosphorylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
T193 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus
T264 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
R326 Methylation PhosphoSitePlus
Y346 Phosphorylation PhosphoSitePlus
S438 Phosphorylation PhosphoSitePlus   UniProt 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T149 A149 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S196 F196 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S253 T253 Biomuta DOID:3571 / liver cancer [ cosmic ]
R326 T326 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]