iPTMnet Report for Q4KMQ2 (ANO6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q4KMQ2 / ANO6_HUMAN
Protein Name Anoctamin-6
Gene Name Name: ANO6
Synonyms:TMEM16F;
Organism Homo sapiens (Human)

PRO ID PR:Q4KMQ2
DAG View
PRO Name anoctamin-6 (human)
Definition An anoctamin-6 that is encoded in the genome of human.
Short Label hANO6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q4KMQ2 (ANO6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S38 Phosphorylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
T160 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
Y279 Phosphorylation PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
C330 Methylation IEDB 31844290
N361 N-Glycosylation GlyGen 29741879, 24190977
N493 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 24190977
K589 Ubiquitination PhosphoSitePlus
S642 Phosphorylation PhosphoSitePlus
K644 Ubiquitination PhosphoSitePlus
K793 Ubiquitination PhosphoSitePlus
N802 N-Glycosylation GlyGen 24190977
Y808 Phosphorylation PhosphoSitePlus
K871 Ubiquitination PhosphoSitePlus
K876 Ubiquitination PhosphoSitePlus
K884 Ubiquitination PhosphoSitePlus
K888 Ubiquitination PhosphoSitePlus
K908 Ubiquitination PhosphoSitePlus
S909 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S155 Phosphorylation HPRD 18491316
S156 Phosphorylation HPRD 18491316
S173 Phosphorylation HPRD 18491316
S909 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S38 * Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K176 R176 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S256 * Biomuta DOID:1324 / lung cancer [ cosmic ]
N361 S361 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
K589 R589 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K793 * Biomuta DOID:1319 / brain cancer [ cosmic ]
K793 N793 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y808 S808 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y808 C808 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K876 N876 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K888 T888 Biomuta DOID:3571 / liver cancer [ cosmic ]