iPTMnet Report for Q4KMQ1 (TPRN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q4KMQ1 / TPRN_HUMAN
Protein Name Taperin
Gene Name Name: TPRN
Synonyms:C9orf75;
Organism Homo sapiens (Human)

PRO ID PR:Q4KMQ1
DAG View
PRO Name taperin (human)
Definition A taperin that is encoded in the genome of human.
Short Label hTPRN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q4KMQ1 (TPRN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K19 Ubiquitination PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
Y126 Phosphorylation PhosphoSitePlus
R192 Methylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
T206 Phosphorylation PhosphoSitePlus
R210 Methylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S245 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
T267 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus   UniProt 23186163
S364 Phosphorylation PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
Y448 Phosphorylation PhosphoSitePlus
K543 Ubiquitination PhosphoSitePlus
S579 Phosphorylation PhosphoSitePlus
S654 O-Glycosylation GlyGen 35132862, 28657654, 35254053
Y710 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R210 W210 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S226 W226 Biomuta DOID:1612 / breast cancer [ icgc ]
S264 R264 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S418 L418 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]