iPTMnet Report for Q4KMP7 (TBC1D10B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q4KMP7 / TB10B_HUMAN
Protein Name TBC1 domain family member 10B
Gene Name Name: TBC1D10B
ORFNames:FP2461;
Organism Homo sapiens (Human)

PRO ID PR:Q4KMP7
DAG View
PRO Name TBC1 domain family member 10B (human)
Definition A TBC1 domain family member 10B that is encoded in the genome of human.
Short Label hTBC1D10B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q4KMP7 (TBC1D10B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation PhosphoSitePlus   UniProt 24275569
T43 O-Glycosylation GlyGen 35138101, 32574038, 34725712, ...35254053, 32119511, 28510447, 28657654
T44 O-Glycosylation GlyGen 35138101, 32574038, 34725712, ...35254053, 32119511, 28510447, 28657654
T46 O-Glycosylation GlyGen 35138101, 32574038, 34725712, ...35254053, 32119511, 28510447, 28657654
S47 O-Glycosylation GlyGen 35138101, 32574038, 34725712, ...35254053, 32119511, 28510447, 28657654
T51 O-Glycosylation GlyGen 35138101, 32574038, 34725712, ...35254053, 32119511, 28510447, 28657654
S111 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
T148 Phosphorylation PhosphoSitePlus
T150 Phosphorylation PhosphoSitePlus
T152 Phosphorylation PhosphoSitePlus
T154 Phosphorylation PhosphoSitePlus
T156 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
T160 O-Glycosylation GlyGen 35138101, 32574038, 34725712, ...35254053, 32119511, 28510447, 28657654
T177 O-Glycosylation GlyGen 32574038
T178 O-Glycosylation GlyGen 35138101, 32574038, 34725712, ...35254053, 32119511, 28510447, 28657654
S181 O-Glycosylation GlyGen 35138101, 32574038, 34725712, ...35254053, 32119511, 28510447, 28657654
T232 Phosphorylation IEDB 32387766
S268 Phosphorylation PhosphoSitePlus
Y269 Phosphorylation PhosphoSitePlus
T304 Phosphorylation PhosphoSitePlus
Y307 Phosphorylation PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
Y315 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
K368 Ubiquitination PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
K433 Acetylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
Y577 Phosphorylation PhosphoSitePlus
T579 Phosphorylation PhosphoSitePlus
K620 Acetylation PhosphoSitePlus
S633 Phosphorylation PhosphoSitePlus
S656 Phosphorylation PhosphoSitePlus
S657 Phosphorylation PhosphoSitePlus
S658 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S661 Phosphorylation PhosphoSitePlus   UniProt 18669648, 19690332, 20068231
K666 Ubiquitination PhosphoSitePlus
S678 Phosphorylation PhosphoSitePlus   UniProt 23186163, 17081983, 24275569, ...18220336
S687 Phosphorylation PhosphoSitePlus   UniProt 23186163, 18669648, 24275569, ...19690332, 20068231
T697 Phosphorylation PhosphoSitePlus
S704 Phosphorylation PhosphoSitePlus
S707 Phosphorylation PhosphoSitePlus
T709 Phosphorylation PhosphoSitePlus
S712 Phosphorylation PhosphoSitePlus
T713 Phosphorylation PhosphoSitePlus
S717 Phosphorylation PhosphoSitePlus
S718 Phosphorylation PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus
S799 Phosphorylation PhosphoSitePlus
Y807 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S656 Phosphorylation HPRD 19651622, 18669648
S657 Phosphorylation HPRD 19651622, 18669648, 20068231
S658 Phosphorylation HPRD 19651622, 18669648, 20068231
S661 Phosphorylation HPRD 19651622, 18669648, 20058876, ...20068231
S678 Phosphorylation HPRD 19413330, 19651622, 18669648, ...15302935, 20058876
S687 Phosphorylation HPRD 19651622, 20166139, 18669648, ...20058876, 20068231
S707 Phosphorylation HPRD 18669648, 20068231
T709 Phosphorylation HPRD 18669648, 20068231
T713 Phosphorylation HPRD 18669648
S717 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T154 S154 Biomuta [ cosmic ]
S158 F158 Biomuta DOID:4159 / skin cancer [ cosmic ]
K398 N398 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S657 C657 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T697 S697 Biomuta DOID:1612 / breast cancer [ cosmic ]
T709 I709 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S718 I718 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]