iPTMnet Report for Q4J6C6 (PREPL)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q4J6C6 / PPCEL_HUMAN
Protein Name Prolyl endopeptidase-like
Gene Name Name: PREPL
Synonyms:KIAA0436;
Organism Homo sapiens (Human)

PRO ID PR:Q4J6C6
DAG View
PRO Name prolyl endopeptidase-like (human)
Definition A prolyl endopeptidase-like that is encoded in the genome of human.
Short Label hPREPL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q4J6C6 (PREPL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
R63 Methylation PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
C160 Methylation IEDB 31844290
K168 Ubiquitination PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
C184 Methylation IEDB 31844290
C227 Methylation IEDB 31844290
S262 Phosphorylation PhosphoSitePlus
T266 Phosphorylation PhosphoSitePlus
T327 Phosphorylation PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
S410 Phosphorylation PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
K426 Acetylation PhosphoSitePlus
K426 Ubiquitination PhosphoSitePlus
K439 Ubiquitination PhosphoSitePlus
Y479 Phosphorylation PhosphoSitePlus
K661 Ubiquitination PhosphoSitePlus
K698 Acetylation PhosphoSitePlus
K704 Acetylation PhosphoSitePlus
K722 Acetylation PhosphoSitePlus
K722 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R63 K63 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
T266 A266 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S410 F410 Biomuta DOID:4159 / skin cancer [ cosmic ]
K698 R698 Biomuta DOID:9256 / colorectal cancer [ cosmic ]